ABSTRACT
Sphenoid sinus represents the body of the sphenoid bone and it has an intimate relation to varies important structures as the internal carotid artery and the optic nerve. Because of this peculiar situation a lot of approaches had been designed to reach the sphenoid sinus [Rosen etal 2006]. The aim of this work is to compare transseptal or transnasal approach as regard safety and conservation of nasal anatomy .This study was conducted upon 20 patients diagnosed to have sphenoid sinus lesion by endoscopic examination and CT scanning, 10 patients underwent transseptal approach and 10 underwent transnasal one. The postoperative results of the two groups were more or less similar as regard the efficacy of the improvement of the complaints but the transseptal approach was found to be superior to the transnasal one in some points