The Establishment of a Wound Model Induced by Ultrapulse CO2 Laser / 대한피부과학회지

BACKGROUND: Wound model is important for the development of dressing materials used in dermatologic practice. Most of the wound healing models are not standardized, individualized ones for each special situation. OBJECTIVES: The purpose of our study is to establish a standardized wound model for evaluating the efficiency of wound healing of dressing material and the effect of epidermal growth factor(EGF) on artificially induced wounds. METHODS: Using ultrapulse CO2 laser and rats, we calibrates the most effective level of energy, frequency, and pulse duration for a wound model of upper dermis. Then, we evaluated the effect of various dressing materials such as vaseline gauze, collagen sponge, collagen sponge containing EGF and hydrogel on wound healing. RESULTS: We obtained relatively even and uniformed wound models of upper dermal level with the setting of ultrapulse CO2 laser; continuous mode, 800watt, frequency of 100Hz, and pulse duration of 0.3ms. Wounds applied with collagen sponge containing EGF showed relatively accelerated wound healing, but wounds with hydrogel or collagen sponge only showed delayed healing of wounds CONCLUSION: Ultrapulse CO2 laser could make a wound model of uniform depth level and could be used as a tool for making standardized wound models.

A Case of Retained Abdominal Pregnancy / 대한산부인과학회잡지

Intra-abdominal pregnancy is uncommon occurrence, constituting only 1% of all ectopic pregnancy. It is usually the result of a tubal or ovarian pregnancy that has aborted or ruptured into the peritoneal cavity. However, the complications of abdominal pregnancy can be devastating. Premature placental separation with massive hemorrhage, hypofibrinogenemia following fetal demise, and suppuration and abscess formation lead to producing maternal health risk. A perinatal mortality and maternal mortality were 85-95% and 0.5-6% respect-ively, from the world literature. Optimal obstetrical care requires early diagnosis and prompt surgical intervention. Recently, a patient presented to the St.Francisco general Hospital with a retained abdominal pregnancy of 6 years duration without complications, as discussed below.

Pulmonary Aspiration and Local Anesthetic Systemic Toxicity following Epidural Anesthesia / 대한마취과학회지

Aspiration can generate postoperative pulmonary morbidity of varing severity, depending on the type and volume of the aspirate. Epidural anesthesia can lead to local anesthetic systemic toxicity with mental change, followed by respiratory depression and abdominal and intercostal muscle weakness depressing the ability of the patient to cough and clear the airway. The authors experienced a case of pulmonary aspiration with systemic toxicity after epidural anesthesia for cesarean section. The chest X-ray showed alveolar consolidation at left lower lung field and arterial blood gases showed that PaO2 decreased. The exact causes of mental change and respiratory depression were unknown, but we suspected it lidocaine induced systemic toxicity due to vascular absorption, When airway reflexes are ineffective during face mask ventilation of the lungs, aspiration of clear oral secretions can generate small airway obstruction.