The tip fracture of the Coopdech bronchial blocker during insertion in the patient with lung surgery / 대한마취과학회지

No abstract available.

A Case of the Sweet's Syndrome Associated with Anti tuberculous Medication / 대한내과학회지

Clinical manifestations of Sweet's syndrome typically include fever, leukocytosis, and tender, erythematous plaques with a dermal infiltration of mature neutrophils. Sweet's syndrome is divided into three clinical categories: idiopathic, malignancy-associated, and drug-induced. No correlation between antituberculous medication and Sweet's syndrome has previously been reported. Here, we describe a 79-year-old woman who developed an acute onset of fever and skin eruption after taking antituberculous medication. The clinical pattern and the result of skin biopsy were consistent with Sweet's syndrome. After cessation of rifampin, the fever and skin rash disappeared. Thus, we diagnosed the patient with Sweet's syndrome, caused by rifampin. To our knowledge, this is the first reported case of rifampin-induced Sweet's syndrome.

Clinical and Histopathological Study of Erythema Nodosum-Like Lesions in Patients with Behcet's Disease / 대한피부과학회지

BACKGROUND: The clinical and histopathological aspects of erythema nodosum-like lesions (ELLs) in patients with Behcet's disease (BD) may resemble those of classic erythema nodosum (EN). Although a few articles that compared ELL and EN in Korean patients have been published in the English literature, there is no comparative study between ELL and EN in the Korean dermatologic literature. OBJECTIVE: The purpose of this study was to evaluate the clinical and histopathological differences between ELL and EN. METHODS: We reviewed all the medical records, photographs and histopathological slides of 33 patients with ELL and 47 patients with EN at our clinic between 2000 and 2009. For all the patients, their diagnosis was confirmed based upon the clinicopathologic correlation and long term follow-up of at least more than 1 year. RESULTS: Compared with EN, ELLs were associated with the following characteristics: a past history of inflammatory plaques and nodules (p=0.037), a relapsing course (p<0.001), dermal infiltration of neutrophils (p=0.001), mixed panniculitis (p<0.001) and subcutaneous vasculitis (p<0.001). In 6 patients (18.2%) the ELLs were the initial major symptom of BD and they didn't have other main symptoms of BD. Compared with the patients with EN, all these patients had inflammatory plaques or nodules on other areas as well as on the lower extremities (p=0.006) and they had a relapsing course (p<0.001). In this group the mean duration of an initial major symptom to the diagnosis of BD was 16.7 months. CONCLUSION: Our results show that ELLs in BD can be distinguished from EN by some clinical and histopathological differences. Especially, in the patient with ELLs without other main symptoms of BD, the occurrence of lesions above the lower extremities and the relapsing course may be important clues to suspect a diagnosis of BD and to exclude a diagnosis of EN.

Milia-like Idiopathic Calcinosis Cutis Occurring in a Toddler Born as a Premature Baby

Milia-like idiopathic calcinosis cutis (MICC) is characterized by smooth, firm, whitish papules resembling milia. Histologically, it appears as a well-defined, round, basophilic nodule within the upper dermis. Although the etiology and treatment remain unclear, it may resolve spontaneously. Some cases have been associated with Down syndrome, and the mean age of MICC patients was 9.9 years old. Herein, we report a rare case of MICC that was not associated with Down syndrome. Noticeably, the patient, a toddler, was born as a premature baby and had an ischemic injury on the right foot at birth. However, the lesions appeared on both feet, including the non-injured left foot. Otherwise he was healthy. After a 21-month follow-up period, the lesions had almost disappeared without any treatment.

Erythematous Granuloma Annulare

Granuloma annulare (GA) is a common, benign, chronic inflammatory disorder, which is characterized by grouped papules in an enlarging annular shape. It has been described in several clinical subtypes, including localized, generalized, subcutaneous, perforating, and erythematous types. Even though generalized, subcutaneous, and perforating types of GA are unusual, there are several reports of those types. However, erythematous or patch GA, has not been reported yet in the Korean literature. Herein, we report a 42-year-old woman with pruritic erythematous patches, which occurred on the extremities without preceding event, and showed typical clinical and histopatologic findings of erythematous GA.

Bullae and Sweat Gland Necrosis in a Non-comatose Patient after Alcohol Intake / 대한피부과학회지

Bullae and sweat gland necrosis is an entity previously reported to occur in comatose patients. Since its first description in comatose patients after carbon monoxide intoxication, similar lesions have also been reported in comatose patients after overdose with several drugs and in immobilized non-comatose patients. To our knowledge, there have been only three occurrences of bullae and sweat gland necrosis after alcohol intake in the Korean dermatologic literature. These cases were never described, but only summarized in a table of an original article. Herein, we more fully describe a case of bullae and sweat gland necrosis in a non-comatose patient after alcohol intake. The case demonstrates conclusively that bullae and sweat gland necrosis can occur not only in a comatose patient but also in a non-comatose patient.

Warty Dyskeratoma Involving Two Adjoining Follicles

Warty dyskeratoma (WD) is a rare epidermal tumor that frequently arises as a papule or nodule on the head or neck of middle-aged or older persons. Histologically, it shows a cup-shaped keratin-filled invagination of an acanthotic epidermis, suprabasilar clefting with villi projecting into the clefts and acantholytic dyskeratotic cells are also present. The changes almost always involve a single hair follicle. We describe a distinctive case of WD that showed involvement of two adjoining follicles within a solitary lesion.

The Koebner Phenomenon in Erythema Multiforme after Getting Acupuncture and Cupping Glass Therapy / 대한피부과학회지

Since its first description in 1887 as the appearance of psoriatic lesions in the uninvolved skin of psoriatic patients as a consequence of trauma, the Koebner phenomenon has been described in numerous diseases. Several types of injury can trigger the Koebner phenomenon, such as physical injury, surgical wound, irritation, sunburn, or radiation therapy. In this report, we describe a 43-year-old woman who developed erythema multiforme which was accompanied by the Koebner phenomenon after getting acupuncture and cupping glass therapy. The purpose of the report is to broaden our awareness of the spectrum of injury that can trigger the Koebner phenomenon.

Actinic Granuloma Showing the Histopathologic Findings of Suppurative Granuloma / 대한피부과학회지

Actinic granuloma is a rare chronic granulomatous dermatosis that is characterized by the elastophagocytosis by multinucleated giant cells. This malady presents in middle-aged individuals and it manifests as asymptomatic papules or annular plaques in the sun-exposed area. There are four main histopathologic patterns of actinic granuloma, including the giant cell, necrobiotic, histiocytic and sarcoidal variants. However, there are no previously reported cases of actinic granuloma associated with the histopathologic findings of suppurative granuloma. We herein report on an unusual case of actinic granuloma that showed the histopathologic findings of suppurative granuloma in a 58-year-old female.

A Case of Fibrous Hamartoma of Infancy with Hypertrichosis on the Axilla / 대한피부과학회지

Fibrous hamartoma of infancy is a rare benign lesion that presents as a solitary, painless, flesh-colored, subcutaneous mass. Most of these lesions occur in the axillary region, the upper arm, the upper trunk, the inguinal area and the external genital area. The lesion histologically consists of three different components in varying proportions: well-defined fibrous trabeculae, primitive mesenchyme and, mature adipose tissue. Overlying skin changes are uncommon, including alternations in pigmentation, eccrine gland hyperplasia and increased hair. To the best of our knowledge, only 6 cases of fibrous hamartoma of infancy with hypertrichosis have been reported. In these six cases, the lesions were located on the buttocks and back, which were non-predilection sites. We report the first case of fibrous hamartoma of infancy with hypertrichosis on the axilla, which is known as a predilection site.

A Case of Woolly Hair / 대한피부과학회지

Woolly hair is normal for most black people, but it is usually abnormal for persons of a non-African or non-Negroid background. A 5-year-old girl visited our clinic complaining of a hair abnormality. Her hair had been tightly curled, fine, and hypopigmented on the entire scalp since birth. Her uncle's son had similar abnormalities of his scalp hairs. On the scanning electron microscopy, the patient's hair revealed cuticular damage with splintering. To the best of our knowledge, this is the first description of a patient with woolly hair who has familial history in Korea.

A Case of Benign Cephalic Histiocytosis / 대한피부과학회지

Benign cephalic histiocytosis is a rare non-Langerhans histiocytosis, which typically presents as a benign self-healing eruption of papules on the head and neck of infants and young children. We report the case of a 13-month-old boy who presented with many reticulated erythematous papules and macules on the face. The histologic examination showed relatively well-circimscribed band-like interstitial and perivascular infiltration of histiocytes, with vesicular nuclei and ample cytoplasms in the upper dermis. Immunohistochemically, the histiocytes were positive for CD68 while lacking expression of CD1a. Approximately 1 year after the first visit, the facial papules became flattened and hyperpigmented.