ABSTRACT
Introduction: Surgical removal of adenoid and tonsils is the most common operation in ENT HandN surgery that principally is operated on patients under 15 years. These tissues are arranged as mucosal defense system that is first defense against different organisms and their Ig[s] productions are quite known. Then, this surgery may have an effect on serum Ig[s] levels
Objective: The purpose of the study was to determine whether adenotonsillectomy actually affected on serum Ig[s] levels
Materials and Methods: This study was an experimental-like type that investigated 300 patients under 15 years at Amiral Momenin Hospital in Rasht that needed these operations. Serum Ig[s] levels were measured immediately before and one month after operation. Ig[s] of serum were measured with SRID [Single Radiation Immune Diffusion]. Adenoid and tonsils were removed with curette and adenotome and incision blunt dissection snare respectively
Results: Serum IgG levels of all patients were the same pre and post-operations. Preoperative serum IgM levels of 289 cases were normal, but 278 ones had normally postoperative levels. In 11 patients, serum IgM levels decreased post operation in 11 patients. IgM levels that were low preoperations in 4 patients were changed to normal levels postoperatively. In 296 patients, serum IgA levels were normal pre and post-operation. In 2 of 4 patients, IgA levels reached normal range postoperatively
Conclusion: Adenotonsillectomy has no significant effect on serum Ig[s] levels