[ effect of intra-articular magnesium sulfate on postoperative acute pain in knee arthroscopy]

Magnesium as an inorganic ion has several products containing it and has a number of therapeutic properties. A very common product, magnesium-sulfate has been proven in field of anesthesiology. This study looks at the effect of intra-articular injection of magnesium-sulfate on acute pain following knee surgery for diagnostic arthroscopy in patients undergoing general anesthesia. 60 patients were selected and divided randomly to 2 groups in this double-blind, randomized, placebo-controlled clinical trial. All anesthesia and surgery methods were the same in both groups. One group received intra-articular magnesium sulfate and the second group received the same volume of placebo. Postoperative pain scores were checked at the 1[st], 3[rd], 6[th], 12[th] and 24[th] hours after the operation by a Visual Analog Scale [VAS] pain assessment scoring system. To present the results Mean [ +/- SD] was used and the P-value less than 0.05 were considered statistically significant. There was no statistically significant difference between the 2 groups for basic variables. Pain reported by the first group who received intra-articular magnesium sulfate solution was significantly less at the 1st hour postoperatively, than the other group [8.7 +/- 1.05 vs 5.53 +/- 1.91, respectively]. Also, at the 6[th] and 12[th] hours postoperatively, the difference was significant [p<0.0001]; but it was not at the 2[nd] 18[th] and 24[th] hours, postoperatively, in comparison to the group who received placebo [p>0.3]. In patients undergoing general anesthesia for arthroscopic knee surgery, intra-articular magnesium sulfate solution significantly reduced pain in the first few hours after the surgery

[Osteoarthritis after open reducation and internal fixation of lisfranc fracture]

Open reduction and internal fixation is the standard surgical approach for lisfranc fracture, however, osteoarthritis is a long term complication. We surveyed the frequency of osteoarthritis after open reduction and internal fixation of lisfranc fracture and its associated factors including accompanied fracture, delayed diagnosis and open or closed fracture. Patients who suffered from lisfranc fracture between 1997 and 2005 and underwent open reduction and internal fixation at least 2 years ago were included. Tarsometatarsal osteoarthritis was investigated among these patients. Of 94 patients, 44 were included with a mean follow up duration of 36 months, among whom, 34 had anatomic reduction while 12 [35.3%] developed osteoarthritis. Meanwhile, of 10 patients with non-anatomic reduction, 8 [80%] developed osteoarthritis. The difference is statistically significant [p=0.004]. Unfortunately, 4 patients [9.1%] were misdiagnosed during the first visit, while 10 [22.7%] patients referred late. Accompanied fractures were reported in 34 [77%] patients. Higher prevalence of osteoarthritis among patients with non-anatomic reduction support the prior theory that open reduction and internal fixation could prevent further degenerative changes in lisfranc joint