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1.
International Eye Science ; (12): 1093-1096, 2005.
Article in Chinese | WPRIM | ID: wpr-641784

ABSTRACT

AIM: To explore the feasibility of combining small pieces of allo-conjunctiva transplantation (ACT) with amniotic membrane transplantation (AMT) to reconstruct ocular surface.METHODS: Bilateral superior bulbar conjunctiva of New Zealand white rabbits were burned by NaOH (1mol/L).After 24h, the right eye (experimental groups Exps) was performed AMT and ACT;the left eye (control groups Cons)was done merely ACT. The viability and function of allografts were identified by PAS staining and scanning electron microscope (SEM) of cytology impression (CI) every week after the operation.RESULTS: In Exps, no obvious rejection was observed.All grafts survived, extended and covered the conjunctival defect. The appearance of grafts, and the shape, number,and function of goblet cells recovered perfectly four weeks after the operation;however, in Cons, obvious rejection was found. Seven grafts were rejected and. symblepharon was observed in those eyes. The appearance of survival allografts were similar to the normal conjunctiva, with similar shape, number and function of goblet cells till the fifth week after the operation. The survival ratet was significantly higher in Exps than in Cons (P <0.05).CONCLUSION: ACT based on AMT can be considered a good way to reconstruct ocular surface for large area conjunctiva alkali burns in early-stage.

2.
Chinese Journal of Plastic Surgery ; (6): 118-119, 2003.
Article in Chinese | WPRIM | ID: wpr-256464

ABSTRACT

<p><b>OBJECTIVE</b>To evaluate a new technique for treatment of the symblepharon caused by physical and chemical burn.</p><p><b>METHODS</b>Thirty-eight patients with 40 eyes were undergoing the treatment. It was carried out to reconstruct the conjunctival fornix by pulling the remained conjunctive backward from the corneal limbus in serious stages.</p><p><b>RESULTS</b>Thirty-eight patients (40 eyes) were treated with this technique, with the successful results of 13 patients (13 eyes) in 2 times, 19 patients (21 eyes) in 3 and 6 patients (6 eyes) in 1. Only one case was failure.</p><p><b>CONCLUSION</b>The above mentioned technique could be a safe and effective way for treatment of symblepharen.</p>


Subject(s)
Humans , Amnion , Conjunctival Diseases , Therapeutics , Eye Burns , Eyelid Diseases , Therapeutics , Plastic Surgery Procedures , Tissue Adhesions , Therapeutics
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