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1.
Shanghai Journal of Preventive Medicine ; (12): 33-36, 2022.
Article in Chinese | WPRIM | ID: wpr-920534

ABSTRACT

Objective To investigate the risk of fatal stroke mortality associated with short-term exposure to air pollution, and to determine the susceptible population. Methods In this study, daily stroke mortalities of adults between 2012 and 2014 in Songjiang District, Shanghai were collected. Time-stratified case-crossover approach was used to assess the association between daily concentrations of air pollutants and fatal stroke mortalities. Results This study included 514 patients who died from acute strokes. The average concentrations during the study period were 77.45 μg·m-3 for PM2.5, 21.22 μg·m-3 for SO2, and 57.59 μg·m-3 for NO2. The fatal stroke mortality of adults under the age of 65 was found to be significantly associated with NO2. At the time of a Lag of 2 d and 03 d, a significantly higher risk of fatal stroke mortality in relation to NO2 exposure was observed, and the OR values of ischemic stroke mortality for people were 3.86 (1.53-9.75) and 5.83 (1.40-24.34) respectively. People over the age of 65 were more sensitive to increased PM2.5 concentrations, at the time of a Lag of 03 d, fatal strokes increased by 28% when PM2.5 levels increased. A significantly higher risk of fatal stroke mortality in relation to increase of NO2 concentration was observed among people who were overweight or obese. Conclusion A significantly higher risk of fatal stroke mortality is associated with the increase of PM2.5 and NO2. The results also suggest that the susceptible population should take additional precautions to avoid or reduce the risk of fatal strokes.

2.
Chinese Journal of Clinical Nutrition ; (6): 296-301, 2017.
Article in Chinese | WPRIM | ID: wpr-668415

ABSTRACT

Objective To explore a method of subsection adjustment for the proportion of three capacity nutrients in patients with metabolic syndrome (MS).Methods Totally 334 MS patients who were diagnosed in the physical examination center and the department of endocrinology and nutrition of Xi'an Central Hospital Affiliated to Xi'an Jiaotong University of School of Medicine were enrolled in this study.According to calculator random digital method,the patients were divided into intervention group (n=168) and the control group (n=166).The energy of two groups were calculated according to the following formula,y =13.5-0.025x1 + 0.215x2-0.006x3+0.342x4-0.268x5+0.623x6 (x1:age,x2:activity intensity index,x3:waist circumference,x4:environmental temperature,x5:BMI,x6:sex).The limit of daily energy was set to 5.02-7.53 MJ.The proportion of the three major nutrients for energy was adjusted of different energy segments of intervention group.When the daily energy was 5.02 MJ,the protein energy ratio was 30%,and the energy increased by 0.42 MJ per time while the protein energy supply ratio was reduced by 2.5%.The energy ratio of carbohydrate was 40%,and the energy increased 0.42 MJ per time while the energy ratio increased by 2.5%.The energy ratio of fat was 30% on various stages of energy supply.The energy proportions of the three major nutrients in the control group were as follows:protein 15%,fat 25%,and carbohydrate 60%.Results After the intervention by 6 months,the 2-hour postprandial blood glucose of intervention group decreased from (9.22±5.57) mmol/L to (6.05±4.68) mmol/L,the hemoglobin A 1 c decreased from (6.79 ± 1.12) % to (5.56± 1.32) %,and the triglyceride decreased from (3.14±1.73) mmol/L to (1.72±1.17) mmol/L.There was significant difference compared with those in control group (P =0.000,0.027,0.034).Conclusion The proportions of the three major nutrients in MS can remarkably improve the glucose and lipid metabolism in MS patients.

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