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Objective To investigate the early enteral nutrition (EN) and total parenteral nutrition (TPN) on the periopera‐tive nutritional status of gastric cancer patients underwent total gastrectomy .Methods 96 cases of total gastrectomy for gastric cancer patients treated in our hospital from January 2011 to March 2013 were randomly assigned ratio EN group and the TPN group ,with 48 cases in each group;nutritional status were compared before and after treatment .Results EN group was superior in nutritional status than TPN group ,it had shorter recover time and less complications (P<0 .05) .Conclusion Early enteral nutri‐tion support can quickly restore the nutritional status of patients and improve the immune status .
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the efficacy and side-effects of high intensity focused ultrasound (HIFU) in the treatment of malignant solid tumors.</p><p><b>METHODS</b>Thirty such patients who refused surgery and or refractory to chemotherapy, were treated by HIFU alone, with the efficacy and side effects monitored in terms of vital organ signs observation, functional assay of important organs, imaging examinations: digital subtraction angiography (DSA), CT, MRI, single photoemission computed tomography (SPECT), large core needle biopsy, complications or metastasis.</p><p><b>RESULTS</b>After HIFU therapy, the vital signs remained stable and the function of heart, lung, kidney and liver was also normal. DSA images showed that small or larger arteries were not damaged. After a follow-up of 10 - 38 months (23.1 months), 26 patients (87%) have been alive. The volume of the tumor underwent complete regression in 10 patients. Shrinkage of tumor volume >/= 50% was observed in 13. Eight of 13 patients were examined by large core needle biopsy, all showing necrosis and/or fibrosis though 3 patients (10%) had local recurrence. Two of these were retreated again by HIFU and the locally recurrent tumor became well controlled. New metastases developed in 5 patients after HIFU therapy. Two patients suffered from peripheral nerve injuries, most of which have recovered during the follow-up. However, one patient developed skin injury.</p><p><b>CONCLUSION</b>High intensity focused ultrasound alone is effective and safe in the treatment of malignant solid tumors.</p>
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Adolescent , Adult , Aged , Female , Humans , Male , Middle Aged , Neoplasms , Therapeutics , Treatment Outcome , Ultrasound, High-Intensity Focused, TransrectalABSTRACT
<p><b>OBJECTIVE</b>To develop a new noninvasive limb-salvaging method in the treatment of primary malignant bone tumor in the extremities.</p><p><b>METHODS</b>Forty-four patients with primary malignant bone tumor were treated by extracorporal high intensity focused ultrasound (HIFU) with or without chemotherapy, with a mean follow-up of 17.6 months.</p><p><b>RESULTS</b>The overall survival and complication rates were 84.1% and 18.2%. In 34 patients with stage II b disease, 30 were disease-free, with 2 died of tumor metastasis to brain and lung and 3 developed local recurrence. In 10 patients with stage III b disease, 5 survived with tumor, with 1 developed local recurrence and 5 died of lung metastasis. Thirty-six of 44 patients were > or = 15 points by Enneking system.</p><p><b>CONCLUSION</b>High intensity focused ultrasound combined with chemotherapy for primary malignant bone tumor in the extremity is proved to be effective and safe, preserving good function in the limbs. HIFU may possibly become a new limb-salvaging treatment for this tumor.</p>