ABSTRACT
Quantum Dots (QDs) with its unique optical properties including broad-range excitation, sizetunable narrow emission spectra and the adjustable emission wavelength by changing the size of core composition, is widely applied in biomedicine as a fluorescent marker in recent years. This paper focuses on the review of the characteristic of ODs, the prospects of its applications in biological and medical areas and the latest research development.Moreover,key issues including the potential toxicity of ODs are discussed.
ABSTRACT
ObjectiveTo investigate the expression and significance of p38 mitogen-activated protei n kinase (MAPK) in autogenous vein graft. Methods Autogenous vein graft model was established by transplanting the right jugular vein to infr arenal abdominal aorta in 80 Wistar rats. Ten vein graft samples were harvested 6 hours, 24 hours, 3 days, 7 days, 2 weeks, 4 weeks, 6 weeks and 8 weeks after s urgery,respectively. Reverse transcription-PCR and in situ hybridization,Wester n blot and immunohistochemistry methods were used to detect the expression of pr otein and phosphorylation protein of p38 and p38mRNA. ResultsThe expression of p38 mRNA increased 6 hours after surgery and reached the peak on the second week after surgery (59%?26%),and significantly higher than that on 4,6,8 weeks( P