ABSTRACT
Objectives: To compare the efficacy of Metformin with insulin in gestational diabetes mellitus in terms of fetomaternal outcome
Study Deign: Randomized clinical trial study
Setting: Lady Aitchison Hospital Lahore
Period: January 2014 to March 2015
Methodology: Total 500 pregnant females with GDM were included in the study through nonprobability, consecutive sampling. Patients were divided into 2 equal groups [A: B]. Patients in group A were given tablet metformin 500 mg by oral route and group B was administrated regular injection Insulin by subcutaneous route
Results: The mean age of females was 32.14 +/- 6.13 years. The mean gestational age was 31.07 +/- 3.8 weeks. There were 78 [15.6%] females who had 0 parity, 107 [21.4%] females had parity 1, 175 [35%] females had parity 2, 95 [19%] females had parity 3, 33 [6.6%] females had parity 4 and 12 [2.4%] females had parity 5.There were 54 [10.8%] cases had PTB, out of which 12 [4.8%] had PTB with metformin while 42 [16.8%] had PTB with insulin. There were 115 [23%] neonates required NICU admission, out of which 37 [14.8%] neonates with metforminand78 [31.2%] neonates with insulin. There were 87 [17%] neonates who had neonatal hypoglycemia, out of which 23 [9.2%] neonates with metformin and64 [25.6%] neonates with insulin. The difference was significant between both groups for all fetal outcomes [P<0.05]
Conclusion: The metformin is more effective in preventing adverse fetal and maternal outcome as compared to insulin
ABSTRACT
Pregnant women are particularly considered to be the most vulnerable group because of the additional demands that are made on maternal stores during pregnancy. The iron deficiency anemia is the most common nutritional deficiency problems in females and is responsible of high maternal death rate in our society
Objectives: to determine the relationship of frequency and severity of iron deficiency anemia to preterm labor and eventual perinatal out come in anemic patients
Study Design: it was a case control study
Study Setting: in Obstetrics and Gynecology Unit-III, Sir Ganga Ram hospital, Lahore from July 2012 to June 2013
Methodology: the study was conducted on 200 patients [100 cases and 100 controls] were studied. Cases were patients admitted in labor room with preterm labor and Controls were females in labor at term at. Convenience sampling was done. On admission relevant history taking examination and investigation were done. The data was collected on a Performa
Results: there were 50 patients with anemia amongst the patients with preterm labor. In the control group, 40 patients were suffering from anemia. In the patients with preterm labor the mean hemoglobin was 9.83 grams/deciliter. In the control group the mean hemoglobin was 10.3gm/dl. [Pregnant women having hemoglobin <10 gm/dl are considered to be anemic]. The odds ratio was calculated to be 3.4 and P value was <0.05
Conclusions: iron deficiency anemia was associated with increased risk for low birth weight, preterm delivery, and perinatal mortality. The frequency of iron-deficiency anemia was seen in both groups of pregnant women
ABSTRACT
A study was carried out over a period of 6 months from June - December 2000 at Lady Aitchison Hospital, Lahore which is affiliated to King Edwards Medical College, Lahore. 100 primigravidae whose gestational period was 36 weeks or above having spontaneous or induced labour were evaluated on a partogram. The study highlighted the value of partogram in the prediction and detection of the likely course of labour
Subject(s)
Humans , Female , Apgar Score , Fetal Distress , Cesarean SectionABSTRACT
A study was carried out at services Hospital Lahore affiliated with postgraduate medical institute Lahore, to rind out incidence, mode of delivery and apgar score in breech presentation. There were total 2432 deliveries of all types during the period of study and out of these 130 were full term breech deliveries, accounting for an incidence of 5.3%. Two groups were formed, Group A and Group B. group. Group A comprised of full term primigravidas with breech presentation and total number of patients was 55. Group B comprised of full term multigravidas with breech presentation and total number of patients was 75. In Group A 45 [81%] patients were delivered vaginally and Group B 60 patients [80%] were delivered vaginally. Incidence of non-elective caesarean section in Group A and B was 7.2% and 6% respectively. Total rate of elective caesarean section was 19%. Morbidity in Group A was 2% and Group B was 3.5°/a. There were no fetal complications. A trend of higher 5 minutes apgar score was positively seen in 100% infants. Caesarean section group was fewer lower apgar infants than groups delivered virginally