ABSTRACT
Background: Hypertension is the one major global burden disease, causes 7.5 million deaths i.e.12.8%. Coronary Heart Disease Prevails 3-4% rural and 8-10% of urban population under 20 year’s age in India. Two fold rise in rural & six fold rise in urban areas since four decades. Environmental and Genetic factors i.e. Sex, BSA, obesity, family history of hypertension, dietary habits, physical activity, stress, race, ethnicity and socio economic status influence on children and adolescent. Many studies have established normal standards of BP for the children of different ages and races in their countries. Indian children cannot be adopted due to differences in ethnic, socio-economic, dietetic, environmental and emotional factors.Methods: A cross sectional study done with 2422 children of 5 to 16 years age school children, selected from 13 Schools (Government and Private) of Urban and Rural areas of Warangal.Results: A linear increase in mean BP with age, sex, weight, height, social status and locality. DBP has strong negative correlation with sex. i.e. female have high DBP and children of lower class and rural area has high DBP. 54 children <85th and 95th percentile and 5 children >95th percentile has comparatively high mean BP, 27 children with history of Hypertension in parents are >85th and 95th percentiles. Positive correlation with BMI in both sexes studied. A multivariate regression study confers positive strong correlation of Mean SBP and DBP with anthropometry.Conclusions: Observed similar results of SBP and DBP in both sexes, linear Increase in mean SBP and DBP with increasing age, weight, height and BMI. Family history of hypertension and high SES had direct correlation to SBP and DBP; class I SES has higher Mean SBP than class III SES.
ABSTRACT
Aim: To study the clinical profile of patients with new onset alcohol related seizures (ARS) Materials and Methods: This was a prospective, hospital based, observational study of 50 consecutive patients without a prior diagnosis of epilepsy presenting with seizures related to alcohol intake, to either emergency room or out–patient department, Department of General Medicine, SVS Medical College, Mahabubnagar, Telangana state, between October 2015 to September 2017. An informed and written consent was taken from the patient or immediate responsible attendant. Detailed history including the personal and family history was obtained from all patients. AUDIT scoring was done in all patients. Detailed examination findings were noted down. EEG and CT Scan Brain was done in all patients. MRI Brain was done when required. Results: A total of 50 patients with alcohol withdrawal seizures were included in the study of which 24(48%) were males and 26(32%) were females. Majority of the patients presented with seizures within 6 days following the last bout of alcohol (85%). All the 50(100%) patients presented with generalized tonic clonic seizures (GTCS) and 8(16%) progressed in to status epilepticus. Withdrawal symptoms were present in 24(48%) patients. Family history of seizures in the first degree relative was present in 4(8%) patients. CT evidence of cortical atrophy was present in 10 (20%) patients. EEG suggestive of seizures was present in 15 (30%) patients. Conclusion: There was a slight female preponderance of alcohol related seizures in this study. Majority presented within 6 days after the last bout of alcohol. All presented with GTCS. EEG and CT Scan Brain reports were normal in majority of the patients.