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1.
Malaysian Journal of Medicine and Health Sciences ; : 119-125, 2024.
Article in English | WPRIM | ID: wpr-1012676

ABSTRACT

@#Introduction: Acute Coronary Syndrome (ACS) is still a major cause of mortality and morbidity globally. One of the factors that cause a prehospital delay is the delay in early detection and inaccuracy of early treatment of ACS. The Internet of Things, which is supported by the high use of smartphones with the DETAK application, can be an opportunity to facilitate ACS education programs so that ACS can be detected early. Method: This study has used a quantitative research design with a quasi-experimental approach which pretest and posttest, in which both the experimental and control groups participate. The inclusion criteria of this study were age >45 years; obesity; smoker; Respondents with a history of: hypertension/diabetes mellitus/hyperlipidemia/hypercholesterolemia/CVD/families with cardiovascular disease. 252 respondents who met the inclusion criteria were randomly divided into control (n=126) and intervention groups (n=126). The intervention group was given education through the DETAK application and the control group was given leaflet about ACS. Results: The results of the study showed that there was an increased in early treatment ability was only found in the intervention group (p<.001). Mean differences of the ability of early detection (p<.001) and early treatment (p=.019)between intervention and control groups were both significance. Conclusion: There is potential for DETAK applications to improve the early detection and treatment capabilities of ACS.

2.
Malaysian Journal of Medicine and Health Sciences ; : 231-236, 2023.
Article in English | WPRIM | ID: wpr-997958

ABSTRACT

@#Introduction: Uncontrolled hypertension is a leading cause of death worldwide and self-care is one of the essential management strategies. However, data regarding the psychometric properties of self-care instruments in the Indonesian context is lacking. This study aims to validate the Hypertension Self-care Profile (HBP SCP) instrument in the Indonesia version. Methods: A forward-backward translation technique was used for the Hypertension (HBP SCP) questionnaire. This questionnaire had three domains namely motivation, self-efficacy, and behavior. It was completed by a total of 191 respondents and the survey was conducted from September to December 2021 in the Health Primary Care Bandung West Java, Indonesia. The Cronbach’s alpha was used to test the reliability scale, the content validity index was assessed by five experts, and item inter-correlation was analyzed to test the total items. Results: The results showed that the content validity index was in the excellent category with a value of 0.89. The Cronbach’s alpha coefficient was 0.875, indicating satisfactory internal consistency. Furthermore, the total items correlation had a significance value of 0.05 (df = N-2) for the three scales namely 0.353-0.742, 0.302- 0.642, and 0.237-0.649 for motivation, self-efficacy, and behavior, respectively. Conclusion: The Indonesian version of the Hypertension HBP SCP instrument is valid and reliable.

3.
Malaysian Journal of Medicine and Health Sciences ; : 3-7, 2023.
Article in English | WPRIM | ID: wpr-997713

ABSTRACT

@#Introduction: The Asthma Knowledge Questionnaire developed by C. Rodriguez Martinez in 2005 was proved to be a valid instrument for asthma knowledge assessment for parents of children with asthma. 17 items were included in the questionnaire including their myths and beliefs, knowledge, and associated aspects. The objective of this study is to analyse the validity and reliability of the Malay version of the questionnaire. Methods: Forward-Backward translation method was used by language experts to obtain the Malay version of the questionnaire. The questionnaire was then given to twenty respondents at the Paediatric Institute Hospital Kuala Lumpur to ensure the clarity and relevance of the questionnaire as a pilot study. Subsequently, 60 respondents who fulfilled the inclusion and exclusion criteria were selected to proceed with the reliability test of the Malay version questionnaire. The results were analysed with SPSS version 26.0. The reliability and internal consistency were confirmed by intra-class correlation and Cronbach’s alpha coefficient. Results: There were 60 respondents to the questionnaire consisting of parents and caretaker who has child with asthma at the Institute of Paediatric Hospital Kuala Lumpur. The mean age of respondents was 34 ± 7.5year old. 91.7% of the respondents were female. The overall Cronbach’s alpha coefficient of the questionnaire was 0.84. Conclusion: The Malay version of the Asthma Knowledge Questionnaire has a good degree of validity, reliability and is culturally acceptable equivalent to the original version.

4.
Malaysian Journal of Medicine and Health Sciences ; : 386-389, 2023.
Article in English | WPRIM | ID: wpr-997707

ABSTRACT

@#In systemic lupus erythematosus (SLE), haematological abnormalities are frequent, although they are an uncommon cause of acquired von Willebrand syndrome (AVWS). AVWS is a rare condition that can cause a bleeding disorder. We presented a case of AVWS in the early diagnosis of SLE. One month before admission, the patient had a history of recurrent epistaxis. He presented to the hospital with symptomatic anaemia and was noted to have severe anaemia with iron deficiency. During hospitalisation, recurrent epistaxis recurred and was found to have prolonged activated partial thromboplastin time (aPTT), presence of lupus anticoagulant (LA), and lower von Willebrand factor (VWF), and factor 8 (VIII) levels. Simultaneously, he was diagnosed with SLE based on Systemic Lupus International Collaborating Clinics (SLICC) criteria. He underwent blood transfusions and was treated with immunosuppressive drugs such as steroids, mycophenolate mofetil, and an anti-fibrinolytic agent; he subsequently stopped bleeding and showed clinical improvement.

5.
Malaysian Journal of Microbiology ; : 1-10, 2023.
Article in English | WPRIM | ID: wpr-988267

ABSTRACT

Aims@#Marine bacteria have been reported to produce potential natural pigment with pharmaceutical properties and their growth can be manipulated in the laboratory to increase pigment production and their antimicrobial activity. Hence, this study aimed to enhance the prodigiosin production in Serratia marcescens IBRL USM84 by improving physical conditions.@*Methodology and results@#The quantification of the pigment produced by S. marcescens IBRL USM84, bacterial cell growth, and its antibacterial activity in the broth medium were determined using a spectrophotometry method. Meanwhile, the antibacterial effect of red pigment on MRSA cells was observed under a scanning electron microscope (SEM). This marine isolate produced the highest yield of prodigiosin (6.95 μg/mL) when cultivated in marine broth with the addition of 0.2% of agar, 25 °C incubation temperature, initial medium pH of 7, 150 rpm of agitation speed for 48 h of cultivation time under light illumination. There was an increment of 151.81% in prodigiosin production after enhancement compared to before the enhancement of cultural conditions. SEM observations revealed that severe damage to the cell’s morphologies was exposed to red pigment as indicated by the formation of small dents, which led to completely collapse and eventually, cell death.@*Conclusion, significance and impact of study@#A positive correlation between pigment production and antibacterial activity was observed in the present study. The results supported the fact that marine bacteria are a reservoir of various pigments with antimicrobial properties. Also, the pigment production by S. marcescens and its antibacterial activity were significantly influenced by physical parameters.


Subject(s)
Prodigiosin , Serratia marcescens , Marine Biology
6.
Malaysian Journal of Nutrition ; : 89-102, 2023.
Article in English | WPRIM | ID: wpr-1005338

ABSTRACT

@#Introduction: There is limited evidence on dietary patterns and the risk of type 2 diabetes (T2D) in women with a history of gestational diabetes mellitus (GDM) compared to their non-GDM counterparts, especially in the Asian population. The pilot study investigated dietary patterns in women with a history of GDM (HGDM) and without a history of GDM (non-HGDM), and the association with T2D risk. Methods: This comparative cross-sectional study involved 64 women (32 HGDM, 32 non-HGDM). Food intake was assessed using a validated food frequency questionnaire. Principal component analysis derived the dietary patterns. T2D risk score was determined using the Finnish Diabetes Risk Score tool. Results: HGDM group had significantly higher proportion of first-degree family history of diabetes; higher risk of T2D and better diabetes knowledge; lower gestational weight gain and postpartum weight retention; and consumed more fast food than nonHGDM. ‘Rice-noodle-pasta-meat’ dietary pattern was significantly associated with increased T2D risk after adjusting for age (β=0.272, p=0.032). ‘Bread-cereals-fast food-meat’ dietary pattern was positively and significantly associated with T2D risk after adjusting for confounders, including age, education level, family history of diabetes, diabetes knowledge score, gestational weight gain, and postpartum weight retention (β=0.251, p=0.012). Conclusion: Dietary patterns high in bread, cereals and cereal products, fast food and meat, as well as rice, noodle, pasta and meat were associated with an elevated T2D risk. A more extensive study is warranted to establish the association between dietary patterns and risk of T2D, focusing on women with a history of GDM.

8.
Rev. bras. cir. cardiovasc ; 36(5): 707-716, Sept.-Oct. 2021. tab, graf
Article in English | LILACS | ID: biblio-1351644

ABSTRACT

Abstract Introduction: Rapid prototyping is a process by which three-dimensional (3D) computerized surface models are converted into physical models. In this study, a 3D heart bio model was created using the rapid prototyping method and the accuracy of this heart model was assessed by clinicians. Methods: The two-dimensional images of normal heart from gated computed tomography scan datasets were used to create a 3D model of the heart. The slices were then processed using the software BioModroid and printed with the 3D printer. The evaluation of the model was performed by a questionnaire answered by four cardiothoracic surgeons, 12 cardiologists, five radiologists, and nine surgical registrars. Results: Eighty-six percent of the anatomy structures showed in this model scored 100% accuracy. Structures such as circumflex branch of left coronary artery, great cardiac vein, papillary muscle, and coronary sinus were each rated 77%, 70%, 70%, and 57% accurate. Among 30 clinicians, a total of 93% rated the model accuracy as good and above; 64% of the clinicians evaluated this model as an excellent teaching tool for anatomy class. As a visual aid for surgery or interventional procedures, the model was rated excellent (40%), good (50%), average (23%), and poor (3%); 70% of the clinicians scored the model as above average for training purpose. Overall, this 3D rapid prototyping cardiac model was rated as excellent (33%), good (50%), and average (17%). Conclusion: This 3D rapid prototyping heart model will be a valuable source of anatomical education and cardiac interventional management.


Subject(s)
Humans , Printing, Three-Dimensional , Tomography, X-Ray Computed , Pilot Projects , Heart , Models, Anatomic
9.
Malaysian Family Physician ; : 124-128, 2021.
Article in English | WPRIM | ID: wpr-875762

ABSTRACT

@#Type 2 diabetes mellitus (Type 2 DM) is a chronic disease which rise is closely linked to the obesity epidemic and which requires long-term medical attention to limit the development of its wideranged complications. Many of these complications arise from the combination of resistance to insulin action, inadequate insulin secretion, and excessive or inappropriate glucagon secretion. The increasing evidence of its remission state has been discussed in the literature. Here we report on a patient with metabolic syndrome who underwent a structured therapeutic lifestyle changes (TLC) therapy which eventually led to remission of Type 2 DM.

10.
Article | IMSEAR | ID: sea-210705

ABSTRACT

Breast cancer is a disease caused by abnormal cell proliferation in the breast. God’s crown fruit (Phaleria macrocarpa)and its seed have potential as an antiproliferation of cancer cells. It contains active compounds such as flavonoids,alkaloids, polyphenols, and tannins. The sample of God’s crown fruit was obtained by extraction and fractionationusing the maceration method. Cytotoxicity of extracts and fractions was determined using Brine Shrimp Lethality Testmethod. Antiproliferation activity test of God’s crown fruit against MCM-B2 was performed using the hemacytometermethod. The God’s crown fruit sample consists of crude ethanol extract, n-hexane fraction, ethyl acetate fraction, andwater fraction. Lethal concentration 50 (LC50) values in crude ethanol extract, n-hexane fraction, ethyl acetate fraction,and water fraction were 13.72, 147.55, 405.81, and 149.55 ppm, respectively. The concentration of the test sample wasdirectly used for the antiproliferation activity test on MCM-B2 cells. God’s crown fruit can act as antiproliferation ofMCM-B2. The smallest concentration of those samples has inhibited MCM-B2 cell proliferation which is 3.5 ppmcrude ethanol extract lower than 100 ppm doxorubicin. The maximum percentage of the antiproliferation activity ofcrude ethanol extract (56 ppm) was able to inhibit MCM-B2 cell proliferation by 58.28% while doxorubicin (100 ppm)by 31.2%. This is due to the fact that crude ethanol extract has a lot of complex polar phytochemical content. The crudeethanol extract compounds inhibit MCM-B2 cell proliferation synergistically

11.
Malaysian Journal of Medicine and Health Sciences ; : 114-116, 2020.
Article in English | WPRIM | ID: wpr-876719

ABSTRACT

@#Haemoglobinopathies presenting with erythrocytosis is relatively rare. The clinicians might mistakenly diagnose such patients with other causes of erythrocytosis such as myeloproliferative neoplasm, etc instead of haemoglobinopathies. Here, we described two cases of haemoglobin variant, namely Haemoglobin Johnstown (Hb Johnstown) and Haemoglobin Bethesda (Hb Besthesda) that were detected following various futile investigations for persistent erythrocytosis. For both cases, the two main screening methods used were capillary electrophoresis (CE) and high performance liquid chromatography (HPLC). Approximately 30% of the high affinity haemoglobin (Hb) are not detected by electrophoresis method, however, in some cases, a variant Hb peak can be seen in chromatography method. Thus, a high index of suspicion of such diagnosis is utmost important as to not to miss the definitive diagnostic test by DNA analysis.

12.
Malaysian Journal of Medicine and Health Sciences ; : 69-74, 2020.
Article in English | WPRIM | ID: wpr-876678

ABSTRACT

@#Introduction: The aim of thalassaemia screening is to reduce thalassaemia syndromes with significant clinical implication. Therefore, detection of α0 thalassaemia with two genes deletion is clinically more important than α+ thalassaemia with one gene deletion. The aim of this study is to determine the mean corpuscular haemoglobin (MCH) cut-off point for α0 thalassaemia screening. Method: A total of 688 α0 and α+ thalassaemia cases confirmed by DNA analysis were analysed. Red cell indices (MCV, MCH, RBC, Hb) were retrieved from the laboratory information system. Receiver operating characteristic (ROC) curve is generated to determine the MCH cut-off point for α0 thalassaemia. The diagnostic performance of MCH cut-off value was evaluated with a validation group comprising 100 samples of alpha thalassaemia carriers. Results: ROC curve analysis with area under the curve (AUC) of 0.969 showed that MCH at cut-off of 23.5pg has high sensitivity and specificity in detecting α0 thalassaemia with 98% sensitivity and 85% specificity. Conclusion: MCH cut-off value of 23.5pg can be adopted as the cut-off point for α0 thalassaemia screening to detect clinically significant thalassaemia syndrome and reduce cost and burden of screening.

13.
Malaysian Journal of Medicine and Health Sciences ; : 58-63, 2020.
Article in English | WPRIM | ID: wpr-876676

ABSTRACT

@#Introduction: Iron deficiency anaemia (IDA) is the most common cause of anaemia. The diagnosis of IDA, however, remains a challenge and is a problem worldwide. Serum iron study is commonly used for IDA diagnosis but there are some limitations. This study was conducted to evaluate reticulocyte-haemoglobin equivalent (Ret-He) as a screening tool for IDA diagnosis in adults. Method: This is a comparative case control study conducted in Hospital Tengku Ampuan Afzan, Kuantan consisting of adult patients with iron deficiency anaemia and a healthy control group. Haematological parameters (Hb, RBC count, MCV, MCH, RDW) inclusive of Ret-He and serum iron parameters (serum iron, transferrin saturation and serum ferritin) were measured. Correlation between Ret-He with other haematological and serum iron parameters were analysed. Results: There were 103 IDA adult patients with majority of them being female (85.4%) with median age of 36 years old. Malay ethnicity (79.6%) contributed to the larger proportion of adult IDA patients. The Ret-He value for patient and control groups were 16.50 ± 4.90 pg and 34.80 ± 1.97 pg, respectively. Ret-He was 89.32% sensitive and 100% specific with 100% positive predictive value (PPV) and 73.11% negative predictive value (NPV) when compared to transferrin saturation. There was significant correlation between Hb, MCH, MCV, RDW and serum iron, transferrin saturation and serum ferritin parameters with Ret-He. Conclusion: Ret-He together with a complete blood count, may serve as an alternative to the serum iron parameters for screening of IDA in adults.

14.
Anatomy & Cell Biology ; : 27-35, 2020.
Article in English | WPRIM | ID: wpr-896642

ABSTRACT

Research in forensic anthropology is recent in Malaysia due to limited access to documented skeletal collections. However, advanced imaging techniques provide virtual bone samples for use in morphometric studies to establish population-specific standards by virtual anthropology. This study examined sexual dimorphism in the subpubic angle using a three-dimensional computed tomography model of the pelvis, in a contemporary Malaysian population. The sample comprised multidetector computed tomography (MDCT) scans of 50 male and 50 female adults. Segmentation of the MDCT scans was performed using 3D Slicer, and four landmarks were acquired using Stratovan Checkpoint for the subpubic angle measurement. The technical error of measurement (TEM), relative TEM, and coefficient of reliability (R) exhibited high reliability in measurements. Results showed that the subpubic angle in males was 68.6°±7.6° and in females 87.4°±6.5°. The subpubic angle in females was significantly larger than in males (P<0.001). Inverse correlation was found between the subpubic angle and age, in both males (r=–0.449, P<0.01) and females (r=–0.385, P<0.01). The overall accuracy of sex estimation using the subpubic angle was 94% (P<0.001). The subpubic angle, with a demarcating point of 78.6°, showed a sensitivity and specificity of 94% in the classification of female individuals. In conclusion, sex estimation using the subpu bic angle is highly accurate, with a high degree of expected sensitivity and specificity in the Malaysian population.

15.
Anatomy & Cell Biology ; : 27-35, 2020.
Article in English | WPRIM | ID: wpr-888938

ABSTRACT

Research in forensic anthropology is recent in Malaysia due to limited access to documented skeletal collections. However, advanced imaging techniques provide virtual bone samples for use in morphometric studies to establish population-specific standards by virtual anthropology. This study examined sexual dimorphism in the subpubic angle using a three-dimensional computed tomography model of the pelvis, in a contemporary Malaysian population. The sample comprised multidetector computed tomography (MDCT) scans of 50 male and 50 female adults. Segmentation of the MDCT scans was performed using 3D Slicer, and four landmarks were acquired using Stratovan Checkpoint for the subpubic angle measurement. The technical error of measurement (TEM), relative TEM, and coefficient of reliability (R) exhibited high reliability in measurements. Results showed that the subpubic angle in males was 68.6°±7.6° and in females 87.4°±6.5°. The subpubic angle in females was significantly larger than in males (P<0.001). Inverse correlation was found between the subpubic angle and age, in both males (r=–0.449, P<0.01) and females (r=–0.385, P<0.01). The overall accuracy of sex estimation using the subpubic angle was 94% (P<0.001). The subpubic angle, with a demarcating point of 78.6°, showed a sensitivity and specificity of 94% in the classification of female individuals. In conclusion, sex estimation using the subpu bic angle is highly accurate, with a high degree of expected sensitivity and specificity in the Malaysian population.

16.
Malaysian Journal of Medicine and Health Sciences ; : 63-66, 2020.
Article in English | WPRIM | ID: wpr-877040

ABSTRACT

@#Introduction: In several studies it was described that ineffective communication during patient handover between the hospital departments or during shift-to-shift transfer result in discontinuity of care, inappropriate treatment, and potential risks of injury for patients. The patient handover is a professional responsibility and accountability related to nursing care. SBAR (Situation - Background - Assessment – Recommendation) method as part of the international patient safety goals(IPSGs) was developed to improve communication breakdown. Knowledge and attitude are essential factors associated with the implementation of patient handover, yet limited research was done on this. The purpose of this study was to examine the relationship between nurse knowledge and attitude toward a patient handover. Methods: A cross-sectional approach was applied in this study. A total of 61 nurses consisting of the head nurse, and team leaders participated in sampling technique done by simple random sampling method from the hospital database. Data collection used a structured questionnaire with a good result of validity and reliability. Univariate and bivariate test were used for data analyzing with Statistical Package for the Social Science (SPSS) Version 18. Results: There is a relationship between nurses' knowledge and attitude toward patient handover with OR 5.280 (1.063-26.227); OR 5.333 (1.351-21.062), respectively and statistically significant (p<0.000). Conclusion: Handover is a dynamic process and impacts directly on patient care. Increasing nurse knowledge and attitude are essential to enhance the implementation of patient handover. Training, seminar and intensive practice are strongly needed to build the culture of patient safety.

17.
Malaysian Journal of Medicine and Health Sciences ; : 38-42, 2020.
Article in English | WPRIM | ID: wpr-876847

ABSTRACT

@#Introduction: Accidents including traffic accidents can occur anywhere, anytime. Around the world, 1.2 million die each year from accidents, and 50 million are injured. Indonesia has the fifth highest rate of accidents. The consequences of unexpected accidents can be life threatening, on an average one traffic accident occurs every 0.5 minutes. Cardiac Pulmonary Resuscitation (CPR) is an individual's skill to save a person's life. This is very important in the first five minutes in a victim's life in many emergency situations. In an emergency, bystander including children in the high school is expected to perform a core role in carrying out CPR. The aim of this study is to determine CPR knowledge in High School. Methods: The type of research is a pre-experimental research by approaching the One Group Pre and Post Test Design. Intervention study using pre and post-test validated questionnaire was conducted among 40 students of Tunas Husada high school that were randomly selected. Data analysis was performed with the Macnemar test. Results: The results of the study obtained p= 0.000 which is less than 0.05, so result of the study reveal significant difference in knowledge before and after health education. Thus, there is an effect of health education in increasing knowledge of first aid in traffic accidents among students at Tunas Husada high school, Kendari. Conclusion: This study identify that majority students has poor knowledge on CPR. Therefore, implementation of basic life-support training for all school children is recommenced.

18.
Malaysian Journal of Medicine and Health Sciences ; : 30-33, 2020.
Article in English | WPRIM | ID: wpr-876845

ABSTRACT

@#Introduction: Chronic kidney disease is a public health problem in the world which is increasing every year. Hemodialysis is one of the methods commonly used for patients with end-stage chronic kidney disease. However, hemodialysis does not cure the disease and requires long term therapy. So, the patient's decision whether to undergo hemodialysis, is crucial. Methods: This study is aimed to identify the factors associated with decision making in patients with end-stage chronic kidney disease undergoing hemodialysis in the Bahteramas General Hospital of Southeast Sulawesi Province, Indonesia. This study is a descriptive-analytic study using a cross-sectional design to observe the relationship between patients' decision making for hemodialysis. Results: A total of 34 patients with end-stage chronic kidney disease were chosen by accidental sampling technique. Analysis of the data was done by the Chi-Square test. The results of this study showed that age, level of knowledge, and family support have a significant relationship with the patient's decision for hemodialysis. The distance of home and economic status showed no relationship with the patient's decision to undergo hemodialysis. Conclusion: Based on the results of this study it can be concluded that age, level of knowledge and family support is related to the patient's decision to hemodialysis in the Bahteramas General Hospital of Southeast Sulawesi Province.

19.
Malaysian Journal of Dermatology ; : 54-56, 2020.
Article in English | WPRIM | ID: wpr-922815

ABSTRACT

@#Histiocytic proliferation of the skin can be categorised into Langerhan and non-Langerhan types. Benign cephalic histiocytosis (BCH) is a rare cutaneous non-Langerhan histiocytosis typically affecting infants and young children. We report a case of benign cephalic histiocytosis in a boy who, at seven months of age, presented with multiple yellowish papular eruptions on his face. Over the course of 18 months, the lesion spread to his trunk and upper extremities, sparing the mucous membranes, palms and soles. There was no systemic involvement identified. A histopathologic examination of the skin lesion showed diffuse infiltration of histiocytes within the superficial dermis intermingled with scattered eosinophils and small lymphocytes. Immunohistochemical studies showed that the histiocytes were diffusely positive for CD68. Langerhan markers CD1a and S100 were negative. The correct distinction between BCH and other histiocytic proliferations of the skin is important because BCH has a self-limiting clinical course with a tendency of spontaneous remission.

20.
Malaysian Journal of Medicine and Health Sciences ; : 126-134, 2020.
Article in English | WPRIM | ID: wpr-829461

ABSTRACT

@#Introduction: Glucose-6-phosphate dehydrogenase (G6PD) deficiency causes red blood cell destruction due to oxidative stress. G6PD is essential for NADPH conversion; which is critical for glutathione reductase to prevent damage to cellular structures. In Malaysia, blood donors are not routinely screened for G6PD deficiency. We hypothesise that G6PD-deficient red blood cells are more likely to haemolyse during storage due to increased oxidative molecules. The objectives of this study were to determine the prevalence of G6PD deficiency among blood donors, describe their characteristics and to evaluate the effects of storage on G6PD-deficient donated blood. Methods: This study was conducted at selected mobile donation centres in Terengganu. Consented blood donors were screened for G6PD status using fluorescent spot tests (FST). G6PD enzyme activities were measured for donors who were G6PD deficient. Effects of storage on haemolysis from G6PD-deficient donors were compared with non G6PD-deficient group. Sixty ml of blood was collected from blood unit to transfer pouch for estimation of haemoglobin (Hb), plasma Hb, percentage of haemolysis and plasma potassium. Serial sampling with a 7-day interval was done from Day 1 to Day 35. Statistical analysis was considered significant if p ≤0.05. Results: A total of 440 blood donors were screened and 12 male donors were found to be G6PD deficient by FST. Enzymatic activities were measured in 11 donors as one donor sample failed to be sent to the centre due to logistic problem. Their enzymatic activities ranged from 1.66-2.93 U/g Hb whereby 6 have severe deficiency and the other 5 were categorised as partial deficiency. Donors were asymptomatic for haemolytic episode. Serial sampling showed there was no significant difference of haemolytic parameters in blood units of G6PD-deficient donors as compared to control (p>0.05). Conclusion: Prevalence of G6PD blood donors in Terengganu mobile centres was 2.7%. G6PD enzyme activities did not correlate with clinical symptoms. Haemolytic parameters were not affected in blood units which were G6PD-deficient.

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