ABSTRACT
Reading is a language skill based on visual modality which recently is addressed as a facilitator of expressive language in children with Down syndrome. The aim was designing a whole word reading protocol and examining its effects on the language skills of Persian - Speaking children with Down syndrome. A whole word reading protocol was developed and was examined through a single- subject study with time-series design. The protocol was made up of 50 pictures of nouns which were used through assessment and treatment. The vocabulary stimuli were selected from the receptive lexicon of each child. Three children with Down syndrome [trisomy 21] participated in the study [3 Females, mean age=6.1 years, mean IQ=44], and each participant received an individualized treatment up to 20 sessions. Visual graphs and C-statistic test were used for data analysis. As a result of the treatment, naming ability of treated words was increased statistically in all children [Z= 2.46>1.64; Z=1.75>1.6; and Z=2.37>1.64]. Whole word reading protocol seems to be effective in improving expressive vocabulary in children with Down syndrome
ABSTRACT
Objectives: To evaluate the prevalence of metabolic syndrome in patients with psoriasis in Yazd, Iran
Design: A cross sectional study conducted among Iranian patients with psoriasis and age and sex - matched controls
Setting: Department of Dermatology, Burn and Accident Hospital, Yazd, Iran
Subjects: A total of 110 patients with psoriasis and 110 nonpsoriasis patients were enrolled in this study
Intervention: Data on age, sex, weight, height, waist circumference and blood pressure of all participants were obtained. Severity of psoriasis was assessed using Body Surface Area [BSA] as mild [< 2% BSA], moderate [3-10% BSA] and severe [>10% BSA]. Fasting venous blood samples were collected and the fasting glucose and lipid levels were measured
Main Outcome Measure: We assessed fasting glucose, lipid profile, blood pressure and metabolic syndrome
Results: The mean ages of the cases and controls were 14.80 +/- 39 years and 14.25 +/- 39 years, respectively. The results showed that hypertension is significantly more common in psoriatic patients compared with controls. There was no significant difference in BMI, diabetes mellitus and hyperlipidemia between two groups. Metabolic syndrome was detected in 27.3% of patients with psoriasis and 20.9% of the patients in control group but this difference was not statistically significant [P value = 0.270]
Conclusion: The results of our study revealed that there is no close association between psoriasis and metabolic syndrome in Yazd
ABSTRACT
Amyloidosis cutis dyschromica [ACD] is a rare form of macular amyloidosis characterized by hypo and hyperpigmented macules. Here we described a 20 year old girl with diffuse hypo and hyperpigmentation since she was four years old. Five other members of her family are also involved. Biopsy of hyperpigmented lesions revealed increase of melanin in the basal layer, pigment incontinence and amorphous eosinophilic masses stained positive with Congo red in the papillary dermis. The histopathologic findings were consistent with amyloidosis cutis dyschromica. Other investigations were normal. Dermatologists should consider amyloidosis cutis dyschromica when visit a patient with diffuse hypo and hyperpigmentation