ABSTRACT
Ectopic pregnancy is a significant cause of maternal morbidityand mortality. It is the leading cause of pregnancy relateddeath in the first trimester and account for 9% of all pregnancyrelated death. Ectopic pregnancy refers to the implantation offertilized ovum on any tissue other than the endometrium of theuterus. The main objective of this study is to evaluate theassociation of Chlamydia trachomatis infection in women withectopic pregnancy. To do so, acase control study wasconducted on 90 patients admitted with ectopic pregnancy inthe inpatient department and early normal pregnancy whocome in antenatal clinical and OPD of dept. of Obstetrics &Gynaecology of BSMMU, DMCH, SSMC MH, Dhaka. Thestudy duration was almost three years from the start of January2006 to July 2009. In the present investigation, the resultsshowed that 13.33% & 16.67% had positive IgM and IgG inectopic pregnancy and only 3.33% had positive IgG in normalpregnancy. Total 9 cases (IgM-4& IgG-5) were positive inectopic pregnancy &only 2 cases were positive in normalpregnancy. The difference was statistically significant.Regarding other variables significant difference was present inoccupation of husband, past medical & surgical history.Contraceptive history showed that there was significantdifference between women of ectopic pregnancy and normalpregnancy in oral contraceptive pill use. Regarding pastobstetric history-repeat ectopic pregnancy was 13.3%.Thusly,chlamydia can cause pelvic inflammatory disease which canresult in scarring of the fallopian, with consequent ectopicpregnancies which can be fatal, have reached to morbidity &mortality. Ectopic pregnancy is an important cause of maternaldeath and still holds a diagnostic challenge.