ABSTRACT
Cognitive impairment can emerge in the earliest phases of multiple sclerosis. It strongly impacts different aspects of multiple sclerosis [MS] patients' lives, like employment, social relationships and the overall quality of life; thus, its on-time recognition and treatment is mandatory. This paper discusses issues, diagnostic methods and treatment options for cognitive dysfunctions in MS. This paper is a descriptive review of the related studies in the recent 10 years, performing a keyword search in the main databases. Cognitive impairment mostly involves aspects of information processing, memory and executive functioning in MS. Neuropsychological tests like MACFIMS and BRB-N are recommended for its assessment. Still, there is no fully efficient treatment for cognitive impairment. Researchers have shown some positive effects, using disease-modifying therapies and cognitive rehabilitation. Depression, pain, fatigue and other factors influencing cognitive functions must be paid attention to. Recognizing cognitive impairment as a major symptom for MS, makes studying this subject one of the priorities in dealing with the disease. Therefore, a consecutive research for identification and management of this part of quality of life in MS patients is obligatory
ABSTRACT
Mental health is one of the most important public health issues, and it has major contribution in decreasing global burden of diseases .the objective of this study was to estimate the point prevalence rate of mental disorders in the population aged 18 years and over in Kashan city in 2009. A classified- randomized sampling method was used. The general health questionnaire and clinical interview were employed to determine of mental disorders. Data were analyzed by using spss v. 16 and OR, and chi-square test. The overall prevalence rate of mental disorders in Kashan was estimated [29%] [female= 35/5%]. The most prevalent disorders were mood disorders and anxiety disorders [9/3%] and [4/7%] respectively. In total five hundred-five [505] individuals with mental disorders, 32.1% had mood disorders, 25.6% had anxiety disorders, 4.2% had psychotic disorders, 3.4% had neurological disorders, 3.4% dissociative disorders and 23.7% had other disorders. In this study 7.8% of subject had one mental disorder at least. The prevalence rate was high in people aged 56-65 years [35.8%] and widow [35.8%], illiterate [42.8%] and unemployed [38.8%]. There were statistically significant differences between genders, education, and occupation and marital status. Mental disorder has a priority for any intention intervention by health policy makers. It should be taken into account for any future agenda by ministry of health