ABSTRACT
Although benign ameloblastomas tend to behave aggressively with a high rate of recurrence. CD10 expression can help in predicting the behavior of these tumors. The aim of this study was to determine CD10 expression in variants of ameloblastomas. The data of thirty already diagnosed cases of ameloblastomas were taken. They were examined microscopically for selecting the sections with maximum epithelial content for immunohistochemical staining for CD10. A semi-quantitative scoring for determining the expression was used. In the present study, the follicular variant of ameloblastoma was the commonest [76.7%] followed by unicystic variant [13.3 %] and plexiform variant [10 %]. In the epithelial component CD10 expression was strongly positive in [76.2 %] and [80 %] showed moderate positivity. All the three cases of plexiform variant showed strong positivity. In unicystic variant [9.5%] were strongly positive and [20 %] were moderately positive. In the stromal component 50 % cases of follicular variant were strongly positive and 85.7 % were moderately positive. In the plexiform variant 25 % were strongly and 14.3 were moderately positive. In the unicystic variant strong CD10 positivity was seen in 25 % of cases. The present study concludes that all variants of ameloblastomas express CD10 positivity which may indicate their biological behavior
ABSTRACT
Immunohistochemical detection of Estrogen Receptors [ER] ? has demonstrated similarity between salivary glands and breast tumors. ER status is being routinely used for breast cancers in predicting response to therapy, suggesting their possible role in tumor management of SGTs. The aim of this study was to determine expression of estrogen receptor ? in salivary gland tumors in both genders and various age groups.The data of 57 already diagnosed cases of salivary gland tumors both benign and malignant were taken. They were examined microscopically for selecting the sections with maximum epithelial con-tent for Immunohistochemical staining for ER ?. Allred scoring system was used for assessing ER positivity.Among 57 cases of salivary gland tumors 34 [59.65%] were benign and 23 [40.35%] were malignant. The ER ? status was found positive in 31/57 [54.4%] of cases. Receptors positivity was present in 22 [65%] of benign and 9/23 [39%] of malignant tumors. The age range was 13-90 years. Maximum positivity for receptors [85.7%] was shown in the youngest age group [21-40 years] as compared to the oldest [above 60] which was 50.0%. Fourteen [56%] males and 17 [53.1%] females showed positivity for the ER expression.Present study concludes that salivary gland tumors, benign or malignant, may express estrogen receptor ? in any gender and age group irrespective of their histological and biological type
ABSTRACT
It was a descriptive cross-sectional study conducted in 2010 to explore various misconceptions and taboos about dental health to see their prevalence in the community and to assess their effects on general dental health. The survey was carried out using convenient sampling technique of 300 adults. A Questionnaire in Urdu language consisting of ten close-ended questions regarding most common myths related to dental health in the community was used. SPSS version 16 was used for data analysis. Most of the respondents were found strong believers of various myths irrespective of their qualification level. The results of this study shows that general population of Rawalpindi believes in various myths regarding teeth and their health which results in poor dental health. This might be due to lack of knowledge about the dentition, dental health and its importance
Subject(s)
Humans , Male , Female , Oral Health , Prevalence , Dentistry , Cross-Sectional Studies , MythologyABSTRACT
The aim of this study was to assess the distribution of caries in the oral cavity and its relationship to risk factors. A total of 115 patients including both males and females were randomly selected for the study. Information about risk factors was collected by face to face interviews. Oral examination was performed to evaluate distribution of caries. Descriptive statistics were used to analyze data. Mean DMFT index of the studied population was calculated to be 5.04. The value was higher in females than males. Prevalence of caries was high in the mandible as compared to maxilla. Most frequently involved teeth were first and second molars and occlusal surface was the commonly affected surface. There was a significant relationship between caries and risk factors. Distribution of dental caries in the oral cavity follows a specific pattern. Risk factors influence the caries susceptibility of the individuals