Association of maternal serum alpha fetoprotein levels with gestational age

The aim of the study was to measure the levels of maternal serum alphafetoprotein [AFP] at an early stage, and study its association with prevailing gestation age for use in diagnosis of foetal abnormalities. Microparticle Enzyme Immuno Assay technique was used for AFP quantification. In pregnant women, correlation co-efficient exhibited a strong relationship among age, values of AFP and gestational weeks [r=0.966]. It was further observed that levels of AFP significantly depended on gestation weeks [t >2.93]