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Journal of China Pharmaceutical University ; (6): 87-92, 2018.
Article in Chinese | WPRIM | ID: wpr-704326

ABSTRACT

We developed a rapid method to detect Cu2+and glutathione(GSH)based on the fluorescence quenching-recovery properties of graphene quantum dots(GQDs),which were synthesized by the gentle oxidation of graphite powder.The results revealed that the fluorescence intensity of GQDs versus concentration of Cu2+and GSH had good linearity, with the detection limits of 0.01 and 0.1 mmol/L, respectively.The fluorescence quenching was linearly proportional to the concentrations of Cu2+ranging from 1.0 to 10.0 mmol/L;the fluores-cence intensity was linearly enhanced with the concentrations of GSH ranging from 0.1 to 1.0 mmol/L.In addi-tion,the method was successfully applied to the determination of real samples with recoveries falling between 93%-101% and 96%-107%,respectively.This method is simple,accurate and precise.There was no interference with other familiar co-existing metal ions and potential materials.

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