Value analysis of ultrasound-guided fine needle and core needle biopsy of cervical lymph nodes in diagnosis / 中国医师杂志

Objective To compare the value of ultrasound-guided fine-needle aspiration (FNA) and core needle biopsy (CNB) in diagnosing benign and malignant cervical lymph nodes.Methods A retrospective analysis was performed on 88 patients who received biopsy for cervical lymph node enlargement from January 2015 to May 2017.FNA (n =39) or CNB (n =49) were performed respectively to compare the sensitivity,specificity and accuracy of the two methods in diagnosing benign and malignant cervical lymph node enlargement.Results 84.6％ (33/39) of FNA cases were successfully collected,and 98％ (48/49) of FNA cases were successfully collected for definite pathological diagnosis (P =0.000).The sensitivity,specificity and accuracy of FNA and CNB in diagnosing malignant cervical lymph nodes were 90.9％ and 97.2％,94.1％ and 100％,92.3％ and 98％,respectively.Compared with FNA,there were statistically significant differences in sensitivity,specificity and accuracy in differentiating benign and malignant lymphatic lesions in cervical enlargement (P ＜0.01).The sensitivity and specificity of FNA and CNB in diagnosing cervical lymph node metastatic carcinoma were 100％ and 100％,95.2％ and 100％.Compared with FNA,there was no statistically significant difference in the sensitivity to the diagnosis of cervical lymph node metastatic carcinoma (P =0.102).Conclusions CNB is superior to FNA in sensitivity,specificity and accuracy in diagnosing cervical lymphadenopathy.However,when metastatic cancer was diagnosed,FNA was not significantly different from CNB in sensitivity (P =0.102),and FNA was recommended as the first choice.

The value of ultrasound-guided biopsy in the diagnosis of benign and malignant solid tumors / 中国医师杂志

Objective To explore the value of ultrasound-guided coarse needle biopsy (US-CNB)in the diagnosis of benign and malignant solid tumors.Methods The clinical data of 317 patients with solid liver lesion detected by US-CNB were reviewed retrospectively.93 cases were diagnosed by pathology after operation,and 196 cases were diagnosed by biopsy,imaging and follow-up.The material satisfaction rate,diagnosis of benign and malignant tumors and postoperative complications were discussed in this study.Results Of the 317 cases,289 cases were successfully taken,28 cases were failed,and the success rate was 91.2％.The overall sensitivity of US-CNB to tumor and non tumor were 98.7％ and 95％ respectively,with the specificity of 95％ and 98.7％ respectively.The positive predictive values were 98.7％ and 95％respectively,and the negative predictive values were 95％ and 98.7％,respectively.No serious complications occurred after puncture.Conclusions Ultrasound-guided coarse needle biopsy is a safe,accurate and effective method to diagnose solid tumors.