ABSTRACT
Objective: to compare postoperative mean pain score of bupivacaine versusplacebo in patients undergoing percutaneous nephrolithotomy
Study Design: an experimental study
Place and Duration of Study: department of Urology, The Kidney Centre, Postgraduate Training Institute [PGTI], Karachi, from November 2014 to December 2015
Methodology: a total of 94 patients who underwent standard percutaneous nephrolithotomy, clinically diagnosed renal stone by CT scan, KUB, X-ray or ultrasound were included in the study. Patients were randomly divided into two groups. Forty-seven patients in-group A were treated with 20ml/50mg of 0.25% bupivacaine; and 47 patient's in-group B were treated with normal saline. Postoperatively, visual analog score was used to assess the pain at 6, 12 and 24 hours. Data was analysed using SPSS version 20.0 and student t-test was applied for comparison between the groups
Results: the average age of the patients was 37.23 +/- 11.31 years. Mean pain score in 24 hours was low in group A as compared to group B [5.22 +/- 0.76 vs. 7.85 +/- 0.78; p<0.001]
Conclusion: bupivacaine infiltration into the nephrostomy tract is a highly effective and safe in postoperative pain management for patients undergoing standard PCNL