ABSTRACT
Objective To explore the prediction of weight loss to the function 1 month after surgery in head and neck cancer (HNC) patients with surgical treatment. Methods During August to November 2017, 122 HNC patients from a tertiary hospital in Chengdu were included and investigated by the General Information Questionnaire and European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30. Results 1 month after surgery, the function scores of HNC patients ranged from 86.67(73.33, 93.33) to 100.00(100.00, 100.00), and the physical function score was the lowest. Patients with weight loss during hospitalization had lower score in physical, role and social function ( P＜0.05). According to the results of Logistic regression analysis, age ( OR=6.262, P＜0.05) and Weight loss during hospitalization ( OR=4.363, P＜0.05) were risk factors for the physical function of HNC patients 1 month after surgery. For social function 1 month after surgery, weight loss during hospitalization ( OR=3.306, P＜0.05) was the risk factor. Conclusions Weight loss during hospitalization in HNC patients with surgical treatment can predict the impairment of function 1 month after surgery. Healthcare providers should pay more attention to perioperative nutritional problems of HNC patients, especially the elder patients, and take effective interventions to control the weight during hospitalization to improve patients′function and quality of life.
ABSTRACT
Objective:To explore the effect of subject-centered informed consent in nursing research.Methods:We adopted the subject-centered informed consent in a pilot study on precision symptom in breast cancer patients.Specific measures were taken included offering training for researchers about skills regarding subject-centered informed consent,standardizing the explanation for the informed consent forms,allowing sufficient time for subjects to read the informed consent forms,encouraging subjects to raise questions to researchers,confirming that the subject were fully informed and understood the contents,subjects and researchers jointly signing,and finally,using the checklist to review the entire process.The questions and feedback about the subject-centered informed consent were statistically analyzed.Results:Almost all of patients(96.67％) were able to read the consent forms by themselves,three subjects raised questions to the researcher after reading the forms,and all subjects in our study were satisfied with the informed consent process.Conclusion:The subject-centered informed consent approach makes sure that the subjects' fights of informed consent are fully respected and is an important measure to ensure subjects' fights of informed consent.