Abnormality of growth regulatory factors in benign prostatic hyperplasia / 中华泌尿外科杂志

Objective To investigate the role of 15 kinds of growth regulatory factors in the pathogenesis of benign prostatic hyperplasia (BPH). Methods 15 kinds of growth regulatory factors involving cell proliferation and apoptosis were studied by immunohistochemistry with computer assisted quantitative image analysis.The mean percent area densities of stroma,epithelium and glandular lumen in BPH were examined by quantitative image analysis. Results Positive relations were found bewteen expressions of basic fibroblast growth factor (bFGF),transforming growth factor ?, fibronectin, type Ⅳ collagen and proportions of stroma (r=0.323?0.278?0.235?0.241,P

The relationship between clinical symptomatic parameters and prostatic histologic compositions in patients with benign prostatic hyperplasia / 中华泌尿外科杂志

0.05),however,there was a close correlation with area densities of stroma ( r =-0.33, P