Cementless shoulder surface replacement with glenoid levelling in posttraumatic glenohumeral arthritis

Degenerative glenohumeral arthritis is a possible complication after traumatic glenohumeral dislocation. Shoulder surface replacement arthroplasty has been established for several decades as a mean to restore comfort and function of the shoulder for many afflictions that derange the normal anatomy. The surface replacement may offer some advantages over the stemmed prostheses. We encountered a case with glenohumeral arthritis following neglected fracture dislocation of the shoulder. Copeland cementless surface replacement together with glenoid levelling was done. Six months postoperatively the constant score was markedly improved [82 points]. The patient showed complete relief of pain with marked improvement of the range of movement of the shoulder. The early results in this patient with the use of Copeland cementless surface replacement for treatment of posttraumatic glenohumeral arthritis together with levelling of the glenoid surface were encouraging. The levelling of the glenoid facilitates the smooth gliding of the prosthesis which in turn improves the range of motion and avoids the replacement of the glenoid with its high risk of future loosening. More cases with longer follow-up to document these findings are necessary

Cementless shoulder surface replacement with glenoid leveling in posttraumatic glenohumeral arthritis. "Case presentation"

Degenerative glenohumeral arthritis is a possible complication after traumatic glenohumeral dislocation. Shoulder surface replacement - arthroplasty has been established for several - decades as a mean to restore comfort and function of the shoulder for many afflictions - that derange the normal anatomy. The surface - replacement may offer some advantages over the stemmed prostheses. We encountered a case with glenohumeral arthritis following neglected fracture dislocation of the shoulder. Copeland cementless surface replacement together with glenoid levelling was done. Six months postoperatively the constant score was markedly improved [82 points]. The patient showed complete relief of pain with marked improvement of the range of movement of the shoulder. The early results in this patient with the use of Copeland cementless surface replacement for treatment of posttraumatic glenohumeral arthritis together with levelling of the glenoid surface were encouraging. The levelling of the glenoid facilitates the smooth gliding of the prosthesis which in turn improves the range of motion and avoids the replacement of the glenoid with its high risk of future loosening. More cases with longer follow-up to document these findings are necessary

Effect of natural antioxidants on lead toxicity in rats; histological and histochemical assessment of the liver

The present study was conducted on 40 adult male albino rats divided into four4 equal groups. Groups I and II were used as controls, they received 1 ml distilled water in group I, or sodium acetate 400 mg/kg/day orally in group II. Group III received lead acetate 400 mg/kg/day orally and group IV received lead acetate plus a combination of the 3 natural antioxidant vitamins E [100 mg/kg/day], A [7500 IU/kg/day] and C [1000 mg/kg/day]. Results showed that, the toxic manifestations of lead in group III, cellular degeneration, proliferation, widening of hepatic sinusoids, infiltration and decreased activity of lactic dehydrogenase [LD], succinic dehydrogenase [SD], and adenosine triphosphatase [ATP-ase] enzymes, were greatly improved in group IV. It can be concluded that the combination of the three antioxidant vitamins [E, A and C] seemed to have a remarkable effect in improving the hazards of lead intoxication

Study of the effects of streptozotocin-induced diabetes mellitus on serum calcium, parathyroid hormone and creatinine clearance in rats

The acute effects of streptozotocin [STZ]-induced diabetes mellitus on serum calcium, parathyroid hormone [PTH] and creatinine clearance were studied in 20 experimental rats compared with 10 normal controls. The results showed significant hypocalcemia, hyperparathyroidism, hypercalciuria and decreased creatinine clearance

Intracerebroventricular [ICV] administration of insulin lowers plasma glucose level in the rat

The effect of the central administration of insulin on plasma glucose and immunoreactive insulin [IRI] in normal and diabetic rats has been determined. Insulin [400 muU/kg/5 mul] was injected into the third cerebral ventricle stereotaxically. Blood samples were taken after 10, 30, and 60 minutes from insulin injections by heart puncture. In normal rats, the central administration of insulin significantly lowered plasma glucose level. A significant increase in plasma IRI level was also evident. Intracerebroventricular insulin-induced hypoglycemia was completely blocked by the prior administration of atropine [100 ug/kg i.p.]. In streptozocin [STZ] diabetic rats, intracerebroventricular injected insulin induced a significant fall in plasma glucose, but plasma IRI was not significantly altered. The role of this central action of insulin on plasma glucose regulation was discussed with special reference to other already known mechanisms