ABSTRACT
Background and Aims: Women with history of gestational diabetes mellitus [GDM] are at risk for developing cardiovascular disease and metabolic syndrome. Carotid intima-media thickness [CIMT] is noninvasive marker of sub clinical atherosclerosis assessment. The aim of the present study was to assess relationship between GDM and increased CIMT
Methods: Twenty women with previous history of GDM and twenty women without it [as a control group] were included in the study. Two groups were matched based on their age, body mass index [BMI] and parity. CIMT was measured one year after delivery in two groups by B-mode sonography and compared with ultrasonic results of CIMT in mid- and late-gestational periods
Results: CIMT in both groups increased in gestational period and decreased after delivery and this diminution was significant at late-gestational period in both groups and also significant at mid-gestational period in women with history of GDM
Conclusion: CIMT was significantly decreased one year after delivery in women with GDM