ABSTRACT
Chylomicronemia syndrome is a disorder passed down through families in which the body does not metabolize lipids. This causes fat particles called chylomicrons to build up in the blood. It is also known as Familial lipoprotein lipase (LpL) deficiency. Chylomicronemia syndrome occurs due to a rare genetic disorder in which the enzyme LpL is broken or missing and it causes accumulation of chylomicrons. This is known as Chylomicronemia. LpL is normally found in adipose tissue and muscle. It helps in the breakdown of lipids. Symptoms may start in infancy and include: Abdominal pain due to pancreatitis, neurological symptoms, xanthomas and failure to thrive. Peripheral smear showed blasts with normocytic hypochromic anemia and thrombocytopenia and the Refrigeration test was positive. We report 3 cases of Chylomicronemia syndrome in the last 2 years.
ABSTRACT
Carcinoma ex pleomorphic adenoma (CXPA) is a rare parotid malignancy and its prognosis is poorer than other parotid malignancies. Invasive tumours tend to behave in a more aggressive fashion. These tumours are seen in patients in the sixth to seventh decades of their life. We present a 38-year-old male with a right-sided parotid gland swelling, which was present for the past 3 to 4 years and gradually increasing in size, with a solitary pulmonary nodule in the left upper lobe. On Fine Needle Aspiration Cytology (FNAC) of the parotid gland, a diagnosis of CXPAwas given. This was confirmed by histopathology as CXPAwith the malignant component of mucoepidermoid carcinoma and ductal carcinoma and with comedo pattern of necrosis.