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1.
Article in English | IMSEAR | ID: sea-22271

ABSTRACT

Sputum samples from pulmonary tuberculosis patients attending a hospital for chest diseases and tuberculosis at Jaipur, India were directly subjected to sensitivity tests to detect drug resistance to streptomycin (S), isoniazid (I), rifampicin (R) and ethambutol (Emb) by slide culture technique. Drug resistance was observed to one or more drug in 19.9 per cent of the patients. I resistant organisms were present in 10.1 per cent of patients, S resistance in 7.6 per cent, R resistance in 3.0 per cent and Emb resistance in 2.6 per cent. Resistance was limited to a single drug in 16.7 per cent patients. Drug resistance was unrelated to age and sex of the patients.


Subject(s)
Adolescent , Adult , Drug Resistance , Ethambutol/pharmacology , Female , Hospitals, Special , Humans , India/epidemiology , Isoniazid/pharmacology , Male , Microbial Sensitivity Tests , Middle Aged , Prevalence , Rifampin/pharmacology , Streptomycin/pharmacology , Tuberculosis, Multidrug-Resistant/epidemiology , Tuberculosis, Pulmonary/epidemiology
2.
Indian Heart J ; 1990 Mar-Apr; 42(2): 109-11
Article in English | IMSEAR | ID: sea-4373

ABSTRACT

Of the 4170 open intracardiac operations performed at our hospital in the last 6 years, 55 (1.3%) were reoperations. Of these failed valve repairs or valve substitutes formed the major group (58%) and the interval between first and second operation ranged from 6 months to 8 years. There were 4 deaths on table and another 6 patients died during their hospital stay giving an early mortality rate of 18 per cent. There was one late death during a follow-up period of 1 month to 3 years. There was no death due to perioperative bleeding complications. We conclude that it should now be possible to perform reoperations with an acceptable mortality and good late functional results.


Subject(s)
Adolescent , Adult , Child , Female , Heart Valve Prosthesis/mortality , Humans , Male , Middle Aged , Mitral Valve/surgery , Prosthesis Failure , Reoperation/mortality , Tricuspid Valve/surgery
7.
Indian J Physiol Pharmacol ; 1984 Apr-Jun; 28(2): 153-8
Article in English | IMSEAR | ID: sea-107525

ABSTRACT

Exercise induced modulations in circulatory T4, T3 and TSH were monitored in 14 healthy euthyroid male volunteers undergoing exercise on a bicycle ergometer at 750 KPM for 20 minutes. TSH response to 100 micrograms TRH was also studied in 4 exercising and 4 resting subjects. Serial blood samples were obtained before, during and after the exercise. Serum T4 exhibited a significant decrease (P less than 0.05) from 9.6 +/- 0.49 microgram/dl (mean +/- SE) to 8.3 +/- 0.47 microgram/dl at 20 min after the termination of the exercise, whereas a significant decrease (P less than 0.01) in T3 levels from 158 +/- 9 ng/dl to 144 +/- 8.2 ng/dl was recorded at 40 min after the termination of the exercise. The basal TSH levels as well as the sensitivity of the pituitary thyroid axis, monitored as overall TSH response, reflected by the sum of TSH values at different time intervals and the maximum rise over the basal levels (delta TSH) remained unaltered after exercise. These observations suggest that hormone secretion by the thyroid and its responsiveness to endogenous TSH are maintained after exercise. The decrease in circulatory T4 and T3 could be due to an increase in degradation of the hormones or may reflect a generalized adaptation phenomenon. The exact mechanism and significance of these alterations remains to be elucidated.


Subject(s)
Adult , Heart Rate , Humans , Male , Physical Exertion , Pituitary Gland/physiology , Thyroid Gland/physiology , Thyroid Hormones/blood , Thyrotropin/blood , Thyrotropin-Releasing Hormone/pharmacology
8.
Indian J Ophthalmol ; 1983 Nov-Dec; 31(6): 797-8
Article in English | IMSEAR | ID: sea-70405
9.
Indian J Physiol Pharmacol ; 1982 Apr-Jun; 26(2): 119-24
Article in English | IMSEAR | ID: sea-106165

ABSTRACT

Alterations in plasma immunoreactive insulin (IRI), human growth hormone (hGH) and blood glucose were studied in five male volunteers undergoing exercise for 20 min on a bicycle ergometer at 750 kpm/min. Plasma IRI and hGH levels before exercise were 4.42 +/- 1.35 micro U/ml (mean +/- SE) and 1.94 +/- 0.88 ng/ml respectively. A significant decrease (p less than 0.01) in plasma IRI was observed at 20 min postexercise and remained at lower levels upto 80 min of observations. hGH levels showed significant increase (p less than 0.05) to a mean value of 7.46 +/- 0.71 ng/ml at 20 min of exercise with a peak value of 16.0 +/- 5.04 ng/ml at 20 min postexercise. Sixty min after termination of exercise, hGH levels returned to pre-exercise values. Blood glucose rose progressively with the increase in the duration of exercise and peak levels were recorded at 20 min of exercise. Sixty min after termination of exercise, blood glucose levels returned to pre-exercise values. These observations suggest that exercise stress can lead to a physiological situation in which circulating insulin and glucose are not exclusively dependent on each other.


Subject(s)
Adult , Blood Glucose/metabolism , Growth Hormone/blood , Heart Rate , Humans , Insulin/blood , Male , Physical Exertion , Stress, Physiological/blood , Time Factors
12.
Hindustan Antibiot Bull ; 1974 May; 16(4): 187-9
Article in English | IMSEAR | ID: sea-2539
15.
J Indian Med Assoc ; 1964 Sep; 43(): 268-70
Article in English | IMSEAR | ID: sea-104732
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