ABSTRACT
Multiple system atrophy (MSA) is a sporadic, progressive neurodegenerative disorder of unknown etiology, characterized by various combinations of autonomic, cerebellar, pyramidal and extra pyramidal signs. Based on the consensus criteria, patients with MSA are classified as MSA-c and MSA-P. MRI plays an important role in the early diagnosis. The characteristic finding hot "cross bun’’ sign is seen in MSA of cerebellar type Here we present a case of MSA-C in 52 years old male patient.
ABSTRACT
Blue nevi can present clinically as blue, gray, brown, or black solitary nodules or plaques on the skin. Histologically, they represent collections of melanocytes and melanophages in the dermis. We presented here a case of a cellular blue nevus in a 20 years old man that presented as an enlarging blue-gray nodule on the right buttock. These cases can be challenging both clinically and histologically because malignant melanoma or malignant transformation of a blue nevus could be considered.