Synthesis and pharmacological studies of new pyridopyrazole derivatives

New derivatives of pyrido [2, 3-c] pyrazoles were prepared. Compounds 4a, 6, 8a, b and 14 were tested along with the previously reported pyranopyrazole derivatives 16-20 on the albino Swiss mice to study their effect on the blood constituents and on the glucose and cholesterol levels. Among the investigated compounds, 4a and 8a were found to be highly potent beside the pronounced activity of the others