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Indian J Physiol Pharmacol ; 1980 Jul-Sep; 24(3): 183-9
Article in English | IMSEAR | ID: sea-107600

ABSTRACT

Studies were carried out with human placental lactogen (hPL) to elucidate its role in regulation of steroidogenesis (progesterone and estrogens) during early pregnancy in humans. Our in vitro studies with early pregnancy placenta under different doses of hPL demonstrated that this hormone could stimulate the synthesis of progesterone as well as estrogens (estrone and estradiol) from their respective precursors.


Subject(s)
Estrogens/biosynthesis , Female , Humans , Placenta/metabolism , Placental Lactogen/physiology , Pregnancy , Pregnancy Trimester, First , Progesterone/biosynthesis , Steroids/biosynthesis , Subcellular Fractions/metabolism , Tissue Distribution
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