ABSTRACT
Community-acquired pneumonia (CAP) is caused by different microorganisms, their frequency varying in each community. Legionella pneumophila has been reported as etiologic agent of CAP. The aim of our study was to determine the incidence of acute infection due to Legionella pneumophila in a group of adult patients in Buenos Aires city. Adults of both sexes with CAP diagnosis were included and two serum samples, acute and convalescence (2-4 weeks apart from each other), were tested to detect antibodies against Legionella pneumophila by indirect immunofluorescence (IFI) (Organon Teknica, NC, USA). Ninety-two of the enrolled patients were evaluable, average age 56 years, 55
) fulfilled the serologic diagnostic criteria for Legionella pneumophila acute infection. None of them were confirmed by microorganism isolation. The actual incidence of CAP caused by Legionella pneumophila in Argentina has not yet been established. It will require studies including larger numbers of patients and the use of simple and sensitive tests, such as Legionella pneumophila urinary antigen detection, to establish the exact role of this pathogen in our community.
Subject(s)
Humans , Female , Adolescent , Adult , Middle Aged , Aged , Aged, 80 and over , Legionnaires' Disease/epidemiology , Legionella pneumophila/isolation & purification , Pneumonia, Bacterial/epidemiology , Argentina/epidemiology , Incidence , Prospective Studies , Community-Acquired Infections/microbiology , Community-Acquired Infections/epidemiology , Pneumonia, Bacterial/microbiologyABSTRACT
La curación sin cirugía de la endocarditis micótica en válvula protésica es raramente descripta. Comunicamos un caso de endocarditis por Candida tropicalis sobre una prótese biológica en posición tricuspídea, en la que se consideró que la cirurgía estaba contraindicada. Se había identificado una gran vegetación sobre la prótesis biológica. Se inició tratamiento antimicótico, observándose mejoría progressiva del cuadro y desaparición de la vegetación a lo largo de 15 meses de seguimiento. El tratamiento completó 2 gr de anfotericina B para continuar luego con fluconazol. Nuestra paciente representa el primer caso de endocarditis en válvula protésica por Candida tropicalis que sobrevive sin cirugía.