ABSTRACT
Abstract Objective: Necrotizing enterocolitis (NEC) is characterized by a rich infiltration of macrophages in the intestines, which is derived from monocytes in the blood. The authors aimed to explore the changing trend of absolute monocyte counts (AMC) over time in NEC infants and to verify whether the reduction of AMC correlates with the severity of NEC and whether it can be used to identify infants who need surgery. Method: The authors collected the clinical data of 66 control and 222 NEC infants. The NEC infants were divided into medical NEC (M-NEC) and surgical NEC (S-NEC). The counting of mono-cyte and their percentage change were compared at the time of birth, before NEC (baseline), the onset of NEC and after NEC (recovery). In addition, the same comparison was made among stages 1, 2 and 3 of Bell's staging, respectively. Results: The authors found that the AMC in NEC infants decreased sharply at the onset. Further comparison was made between 172 cases of M-NEC and 50 cases of S-NEC. It was discovered that the AMC reduced more in S-NEC infants at onset, but it increased more at recovery. In addition, the authors found that among stage 1,2 and 3, stage 3 had the lowest AMC and the largest percentage decrease at the onset. Conclusion: The AMC decreases sharply in NEC infants at onset, and the degree of decline is associated with the severity of NEC. AMC is expected to be a marker of NEC and provide a reference for clinicians in the diagnosis and treatment of NEC.
ABSTRACT
Objective@#To explore the relationship between Internet addiction and depressive symptoms among adolescents, and to provide a scientific basis for preventing depression symptoms.@*Methods@#This study was conducted using a stratified random cluster sample method to select 2 149 junior school students reported Internet addiction and depressive symploms in Jilin Province. Propensity score method and quantile regression model were used to evaluate the association between Internet addiction and depressive symploms.@*Results@#Among the 2 149 participants, 386 (18.0%) were found Internet addictive. Prevalence of Internet addition differed significantly among students with different gender, grade, whether smoking or drinking, whether have corporal punishment from parents, sleep duration and body mass index (P<0.05). Depressive symptom scores differed in students with smoking, corporal punishment from parents and insufficient sleep duration (P<0.05). Quantile regression model found that with the quantile increasing, the risk of Internet addiction was also higher due to depressive symptoms(P<0.05). If Internet addiction occurred, their depressive symptom score would be improved 5.08 points for non-Internet addiction students.@*Conclusion@#Internet addiction shows potential impact on depression symptom students. The effect of Internet addiction increased with depression symptoms severity. The results of present study will provide a scientific basis for improving students mental health in the future.