ABSTRACT
The risk of cardiovascular disease increases with obesity and thereby leads to increase in mortality in obese persons. Excess of adipose tissue causes cardiovascular abnormalities through endothelial dysfunction and insulin resistance. We wanted to study different risk factors for cardiovascular diseases by evaluating anthropometric measurements and lipid profiles in metabolic obese normal weight subjects with cardiovascular diseases. METHODSThis case control study was conducted in Jawaharlal Nehru Medical College, AVBRH Hospital, Wardha. After taking clearance from the Institutional Ethical Committee, 200 cases with cardiovascular disease, and 200 controls without the cardiovascular disease, were selected and their lipid profile and anthropometric measurements were evaluated and compared gender wise. RESULTSThere was significant association of weight in females (56.81 ± 3.94), BMI in males (24.32 ± 0.65), cholesterol in females (177.72 ± 16.93), height (163.15 ± 10.94 in males and 154.81 ± 3.76 in females), lean mass (48.92 ± 7.22 in males and 37.05 ± 7.14 in females), % body fat (22.79 ± 7.23 in males and 35.04 ± 9.73 in females), waist circumference (102.93 ± 1.12 in males and 93 ± 0 in females), Serum HDL (30.12 ± 6.98 in males and 33.45 ± 8.34 in females), triglyceride (156.84 ± 7.28 in males and 161.45 ± 10.34 in females) in both males and females. Whereas weight in males, BMI in females, cholesterol in males and serum LDL in both male and female had a P-value of greater than 0.05 and shows no possible association of these factors in the MONW subjects as a cause of cardiovascular diseases. CONCLUSIONSIn this study, we found that there is a significant association between some factors of anthropometric measurements and lipid profile with MONW. Hence, it was concluded that an early screening will help in identifying persons with high risk of cardiovascular disease, and can be a major contributor in prevention of cardiovascular disease.