ABSTRACT
Rhaponticum unifl orum (L.) and Serratula centauroides (L.) are prospective adaptogenic ecdysteroid-containing plants of Buryatia Republic. Underground organs of Rhaponticum unifl orum (L.) and the grass of Serratula centauroides (L.) may be suggested as a plant material containing ecdysteroids for creation of new adaptogenic remedies. Key words: ecdysteroid, Rhaponticum unifl orum (L.), Serratula centauroides (L.) Adaptogenes possess a specifi c combination of peculiar pharmacological properties: being non-toxic substances these preparations manifest anabolic properties which set condition for physiological stimulation of the protective system functions in the body, i.e. bring the body to the state of non-specifi c increased resistance. Adaptogenes have stimulating effect and promote the increase of the resistance to various unfavorable factors. It is worthy to note that adaptogenic properties are characteristic features of natural preparations or compounds being natural metabolites. Some polysaccharides, vaccines, as well as synthetic preparations – stimulators with “economizing” type of the effect have certain adaptogenic properties which are manifested in the regulation of immune system functions. Nevertheless, specifi c stimulating properties and preventive effect manifested in the preparation of the bodily systems to overloading are the most peculiar features of typical adaptogenes [1,2]. At present the use of ecdysteroid-containig plants for developing new adaptogenic medicinal preparations and tonics are of great interest. Plant ecdysteroids have practical signifi cance: they are contained almost in all plants but the difference in concentration levels reaches 8-9 orders. Only few species are characterized by high content of ecdysteroids. Rhaponticum unifl orum (L.) and Serratula centauroides (L.) are ecdysteroid-containing plants growing in the territory of Buryatia [3]. The aim of the present work is to study the chemical composition of ecdysteroid-containing plants - Rhaponticum unifl orum (L.) and Serratula centauroides (L.).