ABSTRACT
OBJECTIVE:To observe therapeutic efficacy of dexmedetomidine combined with propofol for sepsis infection deliration in patients underwent continuous intravenous blood replacement,and to study pharmacokinetic study. METHODS:60 patients with sepsis infection deliration underwent continuous intravenous blood replacement were selected and randomly divided into observation group and control group with 30 cases in each group. Control group was given propofol 0.5 mg/kg,and observa-tion group given dexmedetomidine and propofol. Therapeutic efficacy of 2 groups were analyzed comparatively,and pharmacoki-netic parameters of propofol were studied. RESULTS:The pharmacokinetic parameters of propofol as elimination half-life period (t1/2β),slow distribution half-life period (t1/2α) were shorter than literature reference value,with statistical significance (P0.05). After treatment,ICDSC score of 2 groups were decreased significantly,with statistical significance(P0.05);the average hospital stay of observation group was significantly shorter than that of control group,with statistical signifi-cance(χ2=6.263 4,P=0.000);the incidence of ADR in control group was significantly higher than the observation group,with statistical significance(P<0.05). CONCLUSIONS:Dexmedetomidine combined with propofol have good effect on sepsis infec-tion deliration in patients underwent continuous intravenous blood replacement,and can reduce the length of hospital stay and the incidence of ADR.
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Objectives:To study the effects of parenteral nutrition in postoperative gastrointestinal carcinoma during perichemotheraputic period. Methods:80 patients with gastro intestinal carcinoma were divided into two groups.One group patients received chemotherapy and the other group patients received both chemotherapy and parenteral nutrition during first chemotharapy period.Then breatments changes each other between groups. Results:The nutritional condition,the concentrations of immunoglobumins and WBC in chemotherapy and parenteral nutrition group were significantly improved than those in chemotherapy group. Conclusions:It is helpful for the patients with gastrointestinal carcinoma to receive parenteral nutrition during postoperative perichemotheraputic period.
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OBJECTIVE:To optimize the decolorization technology of Houttuynia cordata polycose active carbon.METHODS:The decolorization technology of Houttuynia cordata polycose active carbon was optimized using orthogonal experiment with temperature,pH value,stirring time and the content of active carbon as factors and the content of polycose and the decoloring rate as indexes.RESULTS:The optimal decolorization technology was as follows:temperature:below 20 ℃; pH=4.0;the content of active carbon was 0.4%,and the stirring time was 40 min.CONCLUSION:The decoloration technology is applicable for industrialized production.