ABSTRACT
@#The most common oral disease is the dental caries, which is chronic transmissible, losing of hard tissue of teeth, and is very widespread in the world. The annual report of oral health survey of World Health Organization shows that 60-90% of population of developing countries was affected by dental caries. In the press review, the prevalence of dental caries and mean DMFt score among 18 years old were 74.4% and 4.04 in Mexico, 2009; 87.4% and 3.59 in Australia, 2003; and 88.9% and 7.15 in Japan, 1999. In Mongolia, the prevalence of dental caries and mean DMFt score among military students in 1987 were 83.3% and 3.7. There is a few studies among students of School of dentistry. Study population consisted of 115 students, who studied from 3rd to 5th course of School of Dentistry, Mongolian National University of Medical Sciences. Study was done by cross sectional study design from November to December, 2017. We checked up dental status of all students according to recommendation by WHO, 2013. The study was approved by the Medical Research Ethics Committee of the Mongolian National University of Medical Sciences and informed consent was obtained from all students (2017/3-04). The prevalence of dental caries among all students was 100% and mean dental caries score was 8.3±0.3 DMF/t, 3.7±0.3 D/t, 3.8±0.3 F/t, 0.8±0.1 M/t. When we assessed mean DMF/t score by student’s course, it was 8.5±0.5 among 3rd year students, 8.6±0.7 among 4th year and 7.9±0.5 among 5th year (p>0.05). Mean decayed teeth among 3rd, 4th, 5th course students were 4.5±0.5, 4.1±0.6 and 2.8±0.4, respectively (p<0.05). Mean filled teeth was 3.4±0.5, 3.5±0.6, 4.4±0.4 (p>0.05) and missed teeth was 0.7±0.2, 1.0±0.3, 0.7±0.2 (p>0.05) among students respectively above courses. All students, who participated in our study had dental caries and observed declining the number of decayed teeth during the study and the number of filled teeth was increasing.
ABSTRACT
Glucose-6-phosphatase dehydrogenase (G6PD) deficiency is the most common enzyme deficiency in humans, affecting 400 million people worldwide and a high prevalence in persons of African, Middle Asian countries. The most common clinical manifestations are neonatal jaundice and acute hemolytic anemia, which is caused by the impairment of erythrocyte’s ability to remove harmful oxidative stress triggered by exogenous agents such as drugs, infection, or fava bean ingestion. Neonatal hyperbilirubinemia caused by glucose-6-phosphate dehydrogenase (G6PD) is strongly associated with mortality and long-term neurodevelopmental impairment. Aim:To determine a level of glucose-6-phosphate dehydrogenase in healthy neonates.The 76.5% of all participants (n=205) was assessed 4.36±1.15 Ug/Hb in normal reference range of G6PD other 23.5% (n=63) was 0.96±0.51 Ug/Hb with G6PD deficiency. In the both sex, 51.5% of male 0.88±0.46Ug/Hb (n=33) and 47.6%of female (n=30) 0.97±0.55Ug/Hb was assessed with G6PDdeficiency. Developing Jaundice period in number of 63 neonates with G6PD deficiency, 85.7% of neonates (n=54)was in 24-72 hours, 4% of neonates (n=3) was in 5-7 days and there is no sign of jaundice in 9% (n=6).Therefore neonates with G6PD deficiency, 53.9% (n=34)contiuned jaundice more than two weeks.G6PD deficiency was determined in male neonates (51.5%) more than female(47.6%). The 76.5% of all participants (n=205) was assessed 4.36±1.15 Ug/Hb in normal reference range of G6PD other 23.5% (n=63) of all participants was 0.96±0.51 Ug/Hb with G6PD deficiency. It shows that G6PD might be one potential risk of neonatal jaundice and hyperbilirubinemia in neonates in Mongolia.