ABSTRACT
Bone substitute biomaterials can prevent severe root resorptions during orthodontic treatments by induction of new bone formation leading in more healthy periodontal status after treatment. Furthermore, NanoBone[TM] graft offers several advantages to be applied in the surgery defects due to its nanocrystalline hydroxy apatite components and nanosized biomaterial structures. The purpose of this study was to evaluate the tissue reactions in the socket preservation using NanoBone[TM] following orthodontic tooth movement. In this experimental study, 4 dogs were selected of the mixed race following defects preparations in the mesial aspect of the first premolar in each quadrant of the animals. NanoBone[TM] was applied in one side as a case region while the opposite side remained hollow as a control side. The first premolar was moved mesially using orthodontic forces and the orthodontic tooth movement was calculated at different time intervals. When the teeth reached half the way, the animals were sacrificed and the sections were subjected to histopathologic assessments. The orthodontic tooth movement values were analyzed using three-way ANOVA test. The mean overall premolar movement towards canine in the socket filled with NanoBone[TM] was 1.076mm while it was 1.203mm in the control side. No significant differences were noted regarding the graft material, the time and jaw position. Root resoprtion was evident in the pressure regions of both groups and new bone formation was noted in the defects filled using NanoBone[TM]. It was concluded that NanoBone[TM] has osteoconductive properties with the decreased root resoprtion due to the limited tooth movements. Therefore, the tooth can be moved into the NanoBone[TM] graft material and the graft can be used as a substitution for autogenous bone during orthodontic tooth movements
ABSTRACT
Aim and Background: periodontal regeneration is one of periodontal treatments goals that a lot of studies have been conducted on it. Guided tissue regeneration technique [GTR], through the inhibition of epithelial cells and gingival connective tissue immigration, cause PDL fibroblasts proliferation at lesion site and also lead to cementum, bone and PDL reconstruction. Despite successful achievements of this technique in human and animal studies, its application in severe lesions such as furcation involvement grade 111 has not been satisfactory. To promote the level of' treatment success, the application of growth factors as agents for the progression of cells proliferation and immigration and the production of extracellular substance has been suggested. The goal of this article was to review these different factors and conducted researches to present a panorama of modern periodontics
Materials and Methods: articles on growth factors application in periodontal lesions regeneration, up to 2003, were collected from Medline and other medical information banks. More over, a lot of specific cases were studied in dentistry journals
Results: it is concluded that the application of different types of growth factors alone or in combination with each other either allogene or autogene, is able to hasten and motivate periodontal lesions regeneration including: intrabony defects and furcation involvements to more advanced cases such as peri implant bone reconstruction. However, their precise application requires more studies
Conclusion: high-level capability of growth factors in the promotion of periodontal treatments consequences has prouided a favourable background for purposeful researches. So as a promising future in periodontal regenerative methods should be expected
ABSTRACT
Background and aim: gingival recession is a relatively prevalent gingival disorder, which increases with age. The purpose of this study was to compare free gingival graft technique [with citric acid] with subepithelial connective tissue graft in the coverage of denuded root surfaces of CII and CIII Miller
Materials and Methods: ten systemically healthy patients with at least two bilateral recession defects of cII and cIII Miller participated in this study. After oral hygiene instruction and reaching plaque index below 20% and gingival bleeding index below l0 %, patients entered surgical phase. For each patient, the recession was treated using free gingival graft with citric acid on one side [group A] and with subepithelial connective tissue [group B] on the other side randomly. Recession width [RW], recession depth [RD], the width of keratinized tissue [KT], probing depth and probing attachment level were measured before and three months after surgery. The results were statistically analyzed by Mann-Whitney test
Results: keratinized tissue increased significantly after both surgical treatments, however, no significant difference was found between the groups. Furthermore, decrease in RD and RW with subepithelial connective tissue graft technique was significantly more than that with free gingival graft
Conclusion: in agreement with the results of other studies, the present study shows subepithelial connective tissue graft as a more efficient technique for root coverage, as compared with free gingival graft