ABSTRACT
Objective: To compare the ultrasound and mammography results to histopathology reports of breast cancer cases presented in King Khalid hospital, Najran, Saudi Arabia, 2016
Methods: This retrospective cross-sectional analytic study was performed on 105 patients with breast lumps, who were referred to breast clinic King Khalid hospital Najran, during 2016. The patients' information was recorded using a checklist, which included name, code, age, ultrasonography, and mammography results and pathology reports. The results of ultrasonography and mammography were compared with histopathology. The results were analyzed on SPSS [version 16]
Results: The mean age of the patients was 42.3 [ +/- 5] years. Our results showed that in histopathology reports, in [30/105] patients i.e. 28.6% were malignant, 26 patients [24.8% ] biopsy revealed benign disease. Examination with mammogram revealed that, 33/105 i.e. [31.4%] were malignant and 40 cases [38.1%] had benign disease. On ultrasound examination, 21/105 [20%] were malignant and 43[40.1%] had benign disease. The mammography sensitivity was 76.6% and ultrasound sensitivity was 60%. Breast Imaging-Reporting and Data System [BIRADS] by mammogram revealed the categories as follows; category 0 in 21.9%, 2in 11.4%, 3 in 31.4, 4 in 5.7%], 4a in 6.7%, 4b in 4.8%, 4c in1.9%, 5 in 8.6% in 6 in 4.8% and unclear in 2.9% of cases. Retro areolar area was involved in 24.8%, Upper Outer Quadrant in 45.7%, Upper Inner Quadrant in 3.8%, Lower Outer Quadrant in 4.8%, Lower Inner Quadrant in 8.6%, Diffuse involvement in 9.5% and unable to pick in 2.9%. By mammogram, the calcification found revealed 15.2% of examined patients had malignant lesions. Findings of lymph nodes examination by mammogram revealed 5.7% of the examined patients had malignant lesions. Significant difference [P<0.05] regarding the age group was found in pathology and mammogram results
Conclusion: This study showed that mammography is the preferred diagnostic tool in screening early breast cancer patients aged above than 40 years with a higher sensitivity; the results are near to open biopsy. For the younger age group the use of ultrasonography in cases with high breast density is promising