ABSTRACT
To evaluate the serum zinc level of the patients with simple febrile seizure and compare them with febrile children without seizure. This prospective case - control study was performed on 60 patients aged 6 months to 6 years from Apr. 2009 to Jan.2010 in Ghaem, Imam Reza and Dr. Sheikh Hospitals in Mashhad. The serum zinc level was assessed and compared between the cases [30 individuals who suffered from simple febrile seizure] and the controls [30 individuals who had fever without seizure]. Mean serum zinc level was 663.7 micro/l and 758.33 micro/l in the case group and the control group, respectively [P<0.001]. It was revealed that the serum level of zinc was significantly lower in children with simple febrile seizure in comparison with febrile children without seizure