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1.
J Cancer Res Ther ; 2019 Oct; 15(5): 1245-1253
Article | IMSEAR | ID: sea-213517

ABSTRACT

Aim of Study: The report of the task group number 43(TG-43) of AAPM has been known as the most common method to obtain the dose distribution around brachytherapy sources. The error caused by independent obtaining and rounding and combinational error caused by algebraic operations of each TG-43 dosimetry parameters increase the total error in the calculation of the dose distribution around the brachytherapy sources. The aim of the present study is to present and evaluate a matrix-based approach for simplifying and reducing calculation errors. Materials and Methods: In this study, the simulation method with MCNPX code was used to obtain the dose distribution. Four sources were simulated, and the dose matrix around these sources was obtained. Finally, the dose distribution obtained from the matrix-based method was compared with the dose distribution obtained from the method of TG-43 report. Results: There is little difference between the values obtained from the two methods in some points. Absolute mean differences between the values obtained by these two methods were 1.4% for the 60Co, 3.52% for the 137Cs, 2.67% for the 192Ir, and 2.42% for the 103Pd sources. The advantage of the matrix-based method is its simple computing process and less computation time. Conclusion: Considering that the comparison of brachytherapy sources is not raised in calculations of treatment planning systems and also considering the more uncertainty in the calculation of the dose distribution in TG-43 method, it is recommended that dose distribution obtained from matrix-based method be used as input for treatment planning systems.

2.
J Cancer Res Ther ; 2019 Jan; 15(1): 237-244
Article | IMSEAR | ID: sea-213597

ABSTRACT

Aim: The aim of this study is to evaluate soft-tissue composition effect on dose distribution for various soft tissues in radiotherapy with a 6 MV photon beam of a medical linac. Background: The compositions of various soft tissues are different which could affect dose calculations. Materials and Methods: A phantom and Siemens Primus linear accelerator were simulated using MCNPX Monte Carlo code. In a homogeneous cubic phantom, six types of soft tissue and three types of tissue-equivalent materials were defined separately. The soft tissues were muscle (skeletal), adipose tissue, blood (whole), breast tissue, soft tissue (9-component), and soft tissue (4-component). The tissue-equivalent materials included water, A-150 tissue equivalent plastic and perspex. Photon dose relative to dose in 9-component soft tissue at various depths on the beam's central axis was determined for the 6 MV photon beam. The relative dose was also calculated and compared for various MCNPX tallies including *F8, F6, and *F4. Results: The results of the relative photon dose in various materials relative to dose in 9-component soft tissue using different tallies are reported in the form of tabulated data. Minor differences between dose distributions in various soft tissues and tissue-equivalent materials were observed. The results from F6 and F4 were practically the same but differ with the *F8 tally. Conclusions: Based on the calculations performed, the differences in dose distributions in various soft tissues and tissue-equivalent materials are minor but they could be corrected in radiotherapy calculations to upgrade the accuracy of the dosimetric calculations

3.
J Cancer Res Ther ; 2019 Jan; 15(1): 216-222
Article | IMSEAR | ID: sea-213594

ABSTRACT

Aim: The purpose of this study is to measure radiation leakage of Siemens Primus Plus and Siemens Artiste linear accelerators in electron mode and to compare the leakage level with that recommended by the International Electrotechnical Commission (IEC) standard. Materials and Methods: In this assessment, Siemens Primus Plus linear accelerator with 10 cm × 10 cm, 15 cm × 15 cm, and 25 cm × 25 cm applicators was used. The radiation leakage in lateral and vertical directions was measured for Siemens Primus Plus and Siemens Artiste linear accelerators. Results: Data derived from radiation leakage measurement for Siemens Primus Plus and Siemens Artiste linear accelerators in lateral direction from the field edge and in vertical direction from the applicator were reported. The radiation leakage data were then compared with the IEC standard to evaluate in-air field leakage. Conclusion: Comparing the radiation leakage level from fields with the IEC standard for two applicators, the maximum that was occurred for 12 MeV electron beam and applicator size of 10 cm × 10 cm in Siemens Artiste linear accelerator was 2.3%, which is less than the IEC's recommended limit of 10%. It is concluded that the leakage amount is much less than the specified limit and that both of the linear accelerators have high level of safety. Considering the measurement stage, it also needs to be noted that the beam angle affected the radiation leakage level from field edge, and in 25° angle, it is higher than in 0° angle. Comparing radiation leakage from the right side of the field for the two linear accelerators, the amount of leakage for Siemens Primus Plus linear accelerator is more than Siemens Artiste linear accelerator

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