ABSTRACT
Objective: The present observational study was conducted to determine the blood glucose, body mass index, blood pressure and serum cholesterol in psychiatric patients
Study Design: Observational study
Place and Duration of Study: This study was carried out at Psychiatric Clinic, Department of Medicine, Indus Medical College, Tando Muhammad Khan, Sindh from June 2014 to January 2016
Materials and Methods: A sample of 275 new cases suffering from different Psychiatric disorders was selected
Diagnosis of Psychiatric disorders was made by a consultant Psychiatrist. Body weight, height and systemic blood pressure were measured by standard methods. Willing participants were asked to sign a proforma of consent for ethical issues. Data was entered on excel sheet and copied to the SPSS 22.0 for statistical analysis. Analysis was performed at P value of < 0.05
Results: Mean +/- SD age was noted as 47 +/- 11.97 years [p = 0.02]. Male to female ratio was 1.83 vs. 1.0 [p=0.0001]. BMI > 30 was noted in 26.5% of subjects. Of 275 study subjects, normal blood glucose was noted in 79.6% while 20.3% of psychiatric patients showed raised blood glucose levels. Normal and raised blood cholesterol was noted in 65.09% and 34.9% respectively. Psychiatric disorders were correlated with blood glucose and blood cholesterol levels
Conclusion: Psychiatric disorders are a risk factor for raised blood glucose, blood cholesterol, BMI and Systemic hypertension; this predisposes patients for diabetes mellitus and associated morbidities
ABSTRACT
Objective: To study platelet counts [PC], mean platelet volume [MPV] and glycated HbA1 in type 2 Diabetes mellitus [T2DM]
Study Design: Case control study
Place and Duration of Study: This study was conducted at the Department of Medicine, Indus Medical College Hospital, Tando Muhammad Khan, Sindh from March to November 2015
Materials and Methods: A sample of 150 subjects; comprising of Group A- controls [n=50], Group B- controlled diabetics [n=50] and Group C- [n=50] uncontrolled diabetics. DM was diagnosed according to American Diabetes Association. Permission was taken from ethics review committee of institute. Only willing subjects were included after they signed consent proforma voluntarily. Blood pressure, BMI, Blood glucose, Platelet counts, MPV and HbA1c were determined Data was typed on Microsoft excel, and then pasted SPSS 22.0 sheet for statistical analysis. Chi square test, one way ANOV, post-Hoc Tukey Cramer and Pearson's association was used for analysis of data variables. All data was analyzed at Confidence interval of 95% [
Results: MPV was raised in Diabetics in particular with uncontrolled glycemic index as shown in table II. MPV showed negative correlation with platelets was found with MPV [r = -0.27, p=0.03]. MPV was positively correlated with glycated HbA1 [r = 0.78, p= 0.0001]. HbA1c as high as 14.3% was noted in uncontrolled diabetics
Conclusion: The present study reports raised Mean platelet volume in Diabetics in particular uncontrolled diabetics. MPV showed positive correlation with HbA1c and negative correlation with platelet count
ABSTRACT
Objective: The present prospective study was conducted to observe the physiological effects of brisk walk on the systemic blood pressure in hypertensive subjects
Study Design: Observational study
Place and Duration of Study: This study was conducted at Outpatient Department, NICVD-Jinnah Postgraduate Medical Center [JPMC] / Physiology department, BMSI, Karachi from December 2001 to May 2002
Materials and Methods: A sample of 30 diagnosed cases of mild uncomplicated systemic hypertension and 30 healthy controls were selected as per study criteria. Aerobic exercise was explained as of doing regular briskwalking of 30 minutes on alternate days for 60 days. Systolic blood pressure [SBP], diastolic BP [DBP], heart rate [HR] and respiratory rate [RR] were checked at baseline and after 60 days of aerobic exercise. Consent of subjects and approval of ethics committee of institute was observed. Data was analyzed on the SPSS 10.0. Continuous and categoricaldata wasanalyzedbystudent`st-testand Chisquaretestrespectivelyas95%confidenceinterval
Results: Baseline systolic BP, diastolic BP, HR and RR were raised in hypertensive subjects compared to controls [p=0.001]. After 60 days aerobic exercise, the systolic BP, diastolic BP, HR and RR were reduced in hypertensive subjects compared to controls [p >0.05]
Conclusion: The present study concludes that the aerobic exercise improves Systolic blood pressure [SBP], diastolic BP [DBP], heart rate [HR] and respiratory rate [RR] in hypertensive subjects
ABSTRACT
Objectives: This study was undertaken to observe the effects of aerobic exercise on lipid profile in newly diagnosed type 2 diabetic patients
Study Design: Observational study
Place and Duration of Study: This study was conducted at Physiology Department, JPMC Karachi from December 2001 to May 2002
Materials and Methods: 30 adult male subjects with uncomplicated type 2 diabetes were selected from diabetic clinic of JPMC, Karachi. 30 apparently healthy adult male subjects were selected from friends, students and staff members of BMSI, as control. The subjects belonging to diabetic groups were then briefed about exercise protocol, which consisted of a regular brisk walk of 30 minutes on alternate days per week for 60 days
Results: Base line Values of mean HDL-cholesterol serum cholesterol, serum total triglycerides, LDL-cholesterol, and mean fasting blood glucose were significantly different in diabetic group as compared to control group [P<0.001] After aerobic exercise, all the parameters except HDL-C were significantly decreased while HDL-C was significantly increased as compared to the pre-exercise values
Conclusion: Regular aerobic exercises improve blood glucose, TAG, LDLc and cholesterol and increases the HDLc in type 2 diabetic subjects has been concluded by the present study