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Journal of the Korean Pediatric Society ; : 1630-1634, 1993.
Article in Korean | WPRIM | ID: wpr-172090

ABSTRACT

Drug-induced toxic epidermal necrolysis (TEN) is a bullous erythematous disease that is characterized by the appearance of scaled lesions and large sheets of pilling on the skin. A caseof TEN occured in a 10 month old female patient. The characteristic skin lesions of TEN developed after oral administration of carbamazepine for a partial seizure. Thig case consists of prodrome of malaise, fever, anorexia, and conjunctivity followed by erythema & flaccid bullae formation. Diagnosis was confirmed by histologic findings. This patient was treated with a massive systemic corticosteroid, antibiotics, fluid and electrolytes, and topical measures. Authors experienced an extremely rare case of TEN dur to carbamazepine, So report it with a brief review of literature.


Subject(s)
Female , Humans , Infant , Administration, Oral , Anorexia , Anti-Bacterial Agents , Carbamazepine , Diagnosis , Electrolytes , Erythema , Fever , Seizures , Skin , Stevens-Johnson Syndrome
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