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Acta méd. (Porto Alegre) ; 34: [6], 20130.
Article in Portuguese | LILACS | ID: biblio-880741

ABSTRACT

Os tumores estromais gastrointestinais são neoplasias mesenquimais do trato gastrointestinal que expressam a proteína tirosina quinase KIT. Ressecção cirúrgica é o tratamento de primeira linha para GISTs operáveis e localizados, além de contribuir para aumento de sobrevida em metastáticos e recorrentes. Novas linhas de drogas estão surgindo para modificar os padrões clássicos de tratamento.


Gastrointestinal stromal tumors are mesenchymal neoplasms of the gastrointestinal tract that express protein tyrosine kinase KIT. Surgical resection is the first-line treatment for localized and operable GISTs, and contribute to increased survival in metastatic and recurrent disease. New lines of drugs are emerging to modify the classic patterns of treatment.


Subject(s)
Gastrointestinal Neoplasms/drug therapy , Gastrointestinal Neoplasms/surgery
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