ABSTRACT
This study was designed to describe the epidemiology and risk factors for nosocomial infection (NI) in a Brazilian neonatal intensive care unit (NICU). This study was a retrospective cohort from January to December, 2003. All neonates admitted to the NICU. Infection surveillance was conducted according to the NNIS, CDC. Chi-square test and logistic regression model were performed for statistical analyses. The study was conducted at a public, tertiary referral NICU of a teaching hospital in the Northeast of Brazil. A total of 948 medical records were reviewed. Overall NI incidence rate was 34 percent. The main neonatal NI was bloodstream infection (68.1 percent), with clinical sepsis accounting for 47.2 percent, and pneumonia was the second most common NI (8.6 percent). Multivariate analysis identified seven independent risk factors for NIs: birth weight, exposure to parenteral nutrition, percutaneous catheter, central venous catheter or mechanical ventilation, abruptio placentae and mother's sexually transmitted disease (STD). Neonates from mothers with STD or abruptio placentae, those weighing less than 1,500 g at birth or those who used invasive devices were at increased risk for acquiring NI.
Subject(s)
Adult , Female , Humans , Infant, Newborn , Male , Cross Infection/epidemiology , Intensive Care Units, Neonatal/statistics & numerical data , Brazil/epidemiology , Cross Infection/etiology , Epidemiologic MethodsABSTRACT
É relatado o caso clínico de uma paciente de 52 anos, portadora de síndrome de Sjogren (SS), sem associação encontrada com outra doença auto-imune, diagnosticada háá 10 anos e que nos últimos anos apresentou quadro de hipertensão pulmonar (HP) severa. Além de a HP não ser uma complicação comum da SS primária, também são incomuns as alterações de imagens da rede arterial pulmonar (estenose segmentar, grave, na emergência de ambas as arteriais pulmonares principais), que foram encontradas neste caso.