ABSTRACT
A 12-year-old boy presented to us with a diagnosis of disseminated tuberculosis which was made based on a history of prolonged fever, multiple neck swellings and radiological findings of bilateral multiple micronodular opacities. Examination showed a diffuse thyroid gland swelling. He was diagnosed to have papillary thyroid carcinoma with distant metastases to cervical lymphnode on histopathology and to lungs.
Subject(s)
Carcinoma, Papillary/pathology , Child , Humans , Lung/diagnostic imaging , Lung Neoplasms/diagnostic imaging , Lymphatic Metastasis , Male , Thyroid Neoplasms/pathology , Tuberculosis/pathologyABSTRACT
OBJECTIVE: To compare pH and PCO2 values of simultaneously obtained arterial, arterialized capillary, and venous blood samples and also to compare oxygen saturation (ASaO2) measured in arterial blood and oxygen saturation by pulse oximetry (PSaO2). METHODS: Prospective study was done in the children admitted in the Pediatric Intensive Care Unit of Christian Medical College Hospital Vellore, requiring critical care. All the three blood gas samples (arterial, capillary and venous) were taken simultaneously and analyzed. Oxygen saturation by pulse oximetry was also recorded. RESULTS: 50 children aged 14 days to 12 years were included in the study. Arterial and capillary pH values were highly correlated (r2=0.9024, p<0.0001). Out of 16 children with arterial acidosis 9(56%) were identified by capillary blood gas. Arterial and venous pH values also showed good correlation (r2=0.8449, p<0.0001). The PCO2 values of arterial and capillary blood gases were found to be highly correlated (r2=0.9534, p<0.0001). The capillary blood gas accurately reflected the arterial PCO2 in 41 (82%) patients. Arterial and venous blood gas PCO2 values had less correlation (r2=0.5917, p=0.011). The arterial oxygen saturation (ASaO2) and oxygen saturation by pulse oximetry (PSaO2) were correlated moderately (r2=0.7241, p<0.0001). CONCLUSION: Even though arterial blood gas analysis is the gold standard, and when an arterial blood gas sample cannot be obtained, a combination of arterialized capillary blood gas and pulse oximetry can be effectively used in acutely ill children of all ages. Venous samples have a good correlation with arterial samples for pH but are not useful for monitoring blood gas status in acutely ill children.
Subject(s)
Acidosis, Respiratory/blood , Acute Disease , Hypoxia/blood , Arteries , Blood Gas Analysis , Capillaries , Child , Child, Preschool , False Positive Reactions , Humans , Infant , Infant, Newborn , Intensive Care Units, Pediatric , Oximetry/instrumentation , Oxygen/metabolism , Prospective Studies , Reproducibility of Results , Sensitivity and Specificity , VeinsABSTRACT
The advantages of breastfeedng to both the mother and infant are well recognised. In rare instances if breasteding is inadequate or if the sodium content bast milk is high, malnutrition and hypernatraemia can result. A 15 days old exclusively breastfed baby presented with inadequate weight gain. On evaluation, he was found to have hypernatraemia and mother's breast milk showed high sodium concentrations. The infant needed parenteral fluid for correction of dehydration and hypernatraemia. His serum sodium and breast milk sodium of the other of the mother returned to normal gradually. He started gaining weight on exclusive breastfeeds. The present paper describes the case report and brief review of the literature.