ABSTRACT
Duchenne muscular dystrophy (DMD) is the most common childhood muscular dystrophy. Presently, there is no known cure for the disorder. We report an 18-year-old boy with DMD who underwent autologous bone marrow-derived mononuclear cell transplantation intrathecally as well as intramuscularly in specific muscles. The parameters used to assess the patient pre- and postoperatively were creatine phosphokinase levels, electromyography, magnetic resonance imaging (MRI) musculoskeletal system upper and lower limbs and manual muscle testing. On follow-up at six months, he showed significant functional improvements along with improvements in his muscle strength. Clinically, his MRI also showed muscle fiber regeneration with decrease in fatty infiltration.