A new triterpenoid and a new steroid from roots of Vladimiria souliei / 中草药

Objective: To study the chemical compositions from the roots of Vladimiria souliei. Methods: The ethanol extract of the roots of V. souliei was isolated by silica gel, Sephadex LH-20, MCI, HPLC, and C18 reverse-phase column chromatographies. Their physical and chemical structures were elucidated by analysis of NMR and MS spectroscopic data, and the absolute configuration of compound 1 was confirmed by Cu-Kα X-ray crystallographic analysis. Results: Three compounds were isolated from the roots of V. souliei, and named as 25-hydroxy-uvaol (1), vlasoudiol (2), and stigmasterol (3), respectively. Conclusion: Compounds 1 and 2 are identified as new compounds, and compound 3 is isolated from the roots of V. souliei for the first time.