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1.
P. R. health sci. j ; 19(4): 341-344, Dec. 2000.
Article in Spanish | LILACS | ID: lil-334083

ABSTRACT

This is a retrospective study based on a population of 80 patients with connective tissue diseases from the University Hospital of Puerto Rico. Among the population, 62 (77.5) of the patients had Systemic Lupus Erythematosus (SLE), whom we were most interested to monitor. The investigation revealed an incidence of 13.8 of anthiophospholipid syndrone within the general population. Among the patients with SLE it was 12.9, and only 5.5 among the population with other diagnoses. The antibody found with the highest frequency within the systemic lupus erythematosus population was the anticardiolipin IgG (30.6) and lupus anticoagulant (17.7). The antibody frequency among patients with other diagnoses was only 5.5 for lupus anticoagulant and 5.5 for anticardiolipin IgM (the only one found). Among SLE's clinical manifestations, the most frequently found were thrombocitopenia and pregnancy complications.


Subject(s)
Humans , Lupus Erythematosus, Systemic/epidemiology , Hospitals, University , Incidence , Prevalence , Puerto Rico , Retrospective Studies
2.
P. R. health sci. j ; 19(4): 335-339, Dec. 2000.
Article in English | LILACS | ID: lil-334084

ABSTRACT

OBJECTIVE: To determine the most common causes of death among Puerto Ricans with systemic lupus erythematosus. METHODS: Chart and record review of all deaths related to SLE complications from 1960 to 1994 at the University of Puerto Rico Hospital. RESULTS: Out of 662 patients diagnosed with SLE 161 (24) died. There were 151 (94) females and 10 (6) males. Mean duration of disease was 11.5 years. Mean age at death was 37 years. The primary causes of death were infection in 44 (27), uremia in 42 (26), cardiovascular complications in 33 (20), central nervous system complications in 18 (11), and pulmonary complications (other than infectious pneumonia) in 12 (7). CONCLUSIONS: The most common causes of death in SLE were infections and renal disease.


Subject(s)
Humans , Male , Female , Adult , Lupus Erythematosus, Systemic/mortality , Cause of Death , Puerto Rico , Retrospective Studies
3.
Bol. Asoc. Méd. P. R ; 80(7): 241-4, jul. 1988. tab
Article in English | LILACS | ID: lil-68826

ABSTRACT

El propósito de este estudio fue determinar la prevalencia y el grado de severidad de daño a la mucosa gastrointestinal superior en pacientes con artritis reumatoide y osteoartritis recibiendo agentes antinflamatorios no esteroidales con o sin prednisona; y la correlación entre los medicamentos y las anormalidades encontradas. Pacientes de la Clínica de Reumatología fueron escogidos al azar para participar en el estudio. Ochenta y cinco de 123 fueron incluidos. La apariencia endoscópica de la mucosa se clasificó del 0 al 9. Dieciseis pacientes tenían mucosa normal, 69 (81.1%) tenían anormalidades la mayoría mínimas (51.8%). Cincuenta y ocho de 85 pacientes tenían síntomas, 22 (38%) de estos tenían cambios moderados o severos; mientras que solo 3 (11.1%) de 27 asintomáticos tenían cambios moderados o severos. Seis pacientes (6%) tenían úlceras activas. La mayoría de los pacientes recibiendo drogas antireumáticas tenían cambios mínimos en endoscopía, y no se encontró un riesgo mayor para enfermedad severa al añadir prednisona a la terapia de no esteroidales. La prevalencia de úlceras en esta población no fue más alta que en la población general


Subject(s)
Adult , Middle Aged , Humans , Anti-Inflammatory Agents, Non-Steroidal/adverse effects , Arthritis, Rheumatoid/complications , Duodenitis/chemically induced , Gastric Mucosa/drug effects , Gastritis/chemically induced , Intestinal Mucosa/drug effects , Osteoarthritis/complications , Peptic Ulcer/chemically induced , Prednisone , Prednisone/drug therapy , Arthritis, Rheumatoid/drug therapy , Drug Therapy, Combination
4.
Bol. Asoc. Méd. P. R ; 79(6): 230-5, jun. 1987. ilus, tab
Article in English | LILACS | ID: lil-77076

ABSTRACT

Dieciseis pacientes con evidencia angiográfica de arteritis de Takayasu fueron estudiados retrospectivamente. Los hallazgos más comunes al momento del diagnóstico fueron disminución en los pulsos, periféricos e hipertensión arterial. Los resultados de laboratório no fueron específicos. La mayoria de los pacientes respondieron favorablemente a los esteroides y/o inmunosupresores, con un buen pronóstico a largo plazo. Nuestra población de pacientes con arteritis de Takayasu es similar a otras series


Subject(s)
Child , Adolescent , Adult , Humans , Male , Female , Takayasu Arteritis , Prognosis , Puerto Rico , Retrospective Studies
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