Studies on serum and tissue lipid fractions in Bengal gram induced retardation of experimental atherosclerosis.

Serum and tissue lipid levels were studied in rabbits in whom egg yolk was used to induce atherosclerosis and Bengal gram was supplemented in the diet as a lipodiatic agent. Monthly serological and tissue studies were done to assess the levels of total cholesterol, triglycerides and phospholipids and it was found that egg yolk feeding leads to statistically significant increases in all these fractions in the serum, liver, adrenals, heart and aorta. Bengal gram supplementation of the diet led to flattening of the atherosclerotic plaques and showed statistically significant decline in the organs with the exception of the kidney. This study confirms the lipodiatic effect of the bengal gram and its beneficial effect on the atherosclerotic plaque.

Serum lipid and lipoprotein fractions in bengal gram and biochanin A induced alterations in atherosclerosis.

Serum lipids and lipoproteins were studied in rabbits fed on egg yolk supplemented diet to induce hypercholesterolemia. Bengal gram and synthetically pure isoflavone Biochanin A have been used as lipodiatic agents in this study. Rabbits were divided into four groups: Group A were fed on egg yolk supplement alone to form the positive control group, Group B were fed with 40 gms of overnight soaked bengal gram (Cicer arietinum), Group C were fed with 50 mgs of Biochanin A fortnightly, Group D was negative control group fed on pelleted laboratory feed. Serum samples were taken every month and total cholesterol, triglycerides and HDL cholesterol were estimated. The other lipoproteins like LDL cholesterol and VLDL cholesterol were obtained by calculations. The Group B and C showed a significant decrease of their lipids and lipoprotein in comparison to Group A thereby indicating the lipodiatic effect of these two substances. However, HDL cholesterol showed an increase in these two groups thereby proving that an increased HDL cholesterol has a protective effect on the atherosclerotic process.

Perceptions & practices of diabetics in Pondicherry.

The knowledge, attitude and self care regarding diabetes was assessed in 150 diabetics, residing in Pondicherry, using a pre-tested schedule addressing six areas of diabetic self-care. Observations made included the ability of the patients to test, interpret and record the result of urine examination; diet practices; and insulin use. The knowledge, attitude and practices of diabetics were less than satisfactory in all the areas of self-care. Up to 80 per cent had a complication or associated disease. Most of the patients appreciated the need for dietary care or medication, but only 50 per cent regulated their diet. Of the 97 per cent using anti-diabetic agents, some were using them harmfully. Only 10.6 per cent of the patients tested their urine, though 71 per cent were aware of the need for this. Only 34 per cent saw a physician regularly. None of the patients had any formal education regarding diabetes.