ABSTRACT
Hyaline membrane disease is primarily a disorder of preterm infants. Its occurrence in term infants is very uncommon and therefore may escape attention. We describe a term infant who developed severe respiratory distress soon after birth. Diagnosis of hyaline membrane disease was revealed at autopsy.
Subject(s)
Anti-Bacterial Agents/therapeutic use , Diagnosis, Differential , Fatal Outcome , Female , Humans , Hyaline Membrane Disease/diagnosis , Infant, Low Birth Weight , Infant, Newborn , Infusions, Intravenous/methods , Intensive Care, Neonatal , Intubation, Gastrointestinal , Oxygen Inhalation Therapy/methods , Ventilators, MechanicalABSTRACT
Perinatal tuberculosis is insufficiently understood. Its early diagnosis is essential but often difficult as the initial manifestations may be delayed. Improved screening of women at risk and sensitivity of the medical community are necessary. A coherent system of cooperation between the hospital and community services and between pediatricians and adult physicians is indispensable to find the index adult case to break the chain of contagion as well as to offer prophylactic therapy to the children at risk. We hereby report a baby with perinatal tuberculosis who was not offered any prophylactic therapy inspite of the mother being diagnosed to have pulmonary tuberculosis.
Subject(s)
Adult , Antitubercular Agents/therapeutic use , Failure to Thrive , Female , Humans , Infant , Infectious Disease Transmission, Vertical , Male , Pregnancy , Pregnancy Complications, Infectious/diagnosis , Tuberculosis, Pulmonary/diagnosisABSTRACT
A young male child presented with hypospadias. Examination revealed additional anomalies including hypertelorism and upslanting of palpebral fissures, suggesting a diagnosis of hypospadias-hypertelorism syndrome. The case is reported because of its rarity and some unusual features.
Subject(s)
Child, Preschool , Facies , Humans , Hypertelorism , Hypospadias , Male , SyndromeSubject(s)
Adult , Cardiac Complexes, Premature/diagnosis , Female , Fetal Heart/physiology , Humans , Infant, Newborn , Pregnancy , Prenatal Diagnosis , PrognosisSubject(s)
Arm/innervation , Brachial Plexus/physiology , Child , Humans , Muscle Contraction/physiology , Reflex, StretchSubject(s)
Addison Disease/blood , Adrenocorticotropic Hormone/blood , Anti-Inflammatory Agents/therapeutic use , Drug Monitoring/methods , Esophageal Achalasia/blood , Glucocorticoids/deficiency , Humans , Hydrocortisone/blood , Lacrimal Apparatus Diseases/blood , Prednisolone/therapeutic use , SyndromeABSTRACT
OBJECTIVE: To determine the clinical profile of children with Henoch-Schonlein purpura (HSP). DESIGN: Hospital based descriptive follow-up study. SUBJECTS: 45 patients attending the Pediatric Rheumatology and Immunology clinic over the last 4 years. RESULTS: The patients were aged between 2.5-12 years with a male to female ratio of 2:1. All cases had palpable purpura. Gastrointestinal involvement was seen in 38 patients, with abdominal pain in 35 (78%) and lower GI bleed in 21 (47%). Large joint arthritis occurred in 60%. Renal involvement was seen in 14 subjects (31%). Major renal involvement occurred in 9 patients, with nephritic syndrome in 6 and nephrotic syndrome in 3 cases. Five patients had minor urinary abnormalities; 6 patients with major renal involvement and crescentic glomerulonephritis were treated with high dose pulse steroid therapy followed by oral prednisolone and azathioprine for 12-18 months. Normalization of urinary abnormalities occurred in these patients over 4-8 months and presently all are normotensive and off antihypertensive drugs. CONCLUSIONS: HSP in children is a common form of vasculitis. Though short term results in HSP nephritis have been good, long term prognosis in those with major renal involvement would remain guarded.