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1.
J. coloproctol. (Rio J., Impr.) ; 43(4): 271-275, Oct.-Dec. 2023. tab, ilus
Article in English | LILACS | ID: biblio-1528943

ABSTRACT

Context: Hirschsprung's disease (HD) is one of the commonest problems requiring surgery in children. More than 95% of children present during new-born period, when they are treated with leveling colostomy and are followed with pull-through surgery a few months later, once the child has gained adequate weight to withstand a major surgery. The commonest pull through surgery done is the Duhamel retro-rectal pull-through (DRPT) repair. Settings and Design: This is a retrospective study of children who presented to one unit in our institute, a tertiary care referral hospital for children less than 12 years, with HD and underwent DRPT procedure during the period between July 2017 to June 2020. The children were evaluated after three years of follow-up for fecal incontinence and constipation. The study was conducted in children diagnosed with classical segment recto-sigmoid HD who underwent surgery. The children who were diagnosed with HD other than classical segment, who underwent primary pull through surgery and who underwent other repairs for HD were excluded from the study. Results: Thirty-two children underwent DRPT procedure during the study period. Of them, five (15.6%) children were lost on follow-up and one (3.1%) child had expired in the immediate post-operative period. Twenty-six children were included in the study. The bowel function score was calculated. The mean age of definitive surgery was 4.2 years. The follow-up period was a minimum of three years. Only two children had a "good" score of eighteen and above. Nineteen children had a "fair" score of 13-17. Five children had a "poor" score of less than thirteen, and among them, two had a "very poor" score of less than nine. The mean BFS was 13.72. Conclusions: Functional outcomes following Duhamel procedure are satisfactory, with 7.7% of children are in the fringe of requiring another surgery for constipation and pseudo-incontinence. (AU)


Subject(s)
Humans , Male , Female , Treatment Outcome , Colon/surgery , Hirschsprung Disease/therapy , Quality of Life , Health Profile , Retrospective Studies , Defecation
2.
Article | IMSEAR | ID: sea-217401

ABSTRACT

Background: Bibliometric studies help in quantifying the pattern of research published in a particular area of interest to get the measure of research productivity. In this context, we analyzed the dental and COVID-19 re-search papers published from December 2019 to January 2021 globally. Method: The articles were retrieved from the PubMed and WHO COVID -19 databases using MeSH terms and keywords. The data downloaded as excel and extracted bibliometric information’s and analyzed using Epi-info (7.2) software. Result: We obtained 800 research articles after removing duplicates and non-relevant articles from 1,823 ar-ticles from these two databases. The articles were published by 475 institutions in 62 countries. Among the listed countries, more publications were done by the United States of America (USA) (n=135;16.8%). The ma-jority of the papers were published in June 2020 (n=114). The King's College London had the most number of publications (n=15; 1.9%). The majority of the articles were original articles (n=592; 74%). Conclusion: The study reports a gradual increase in publications over the months and a slowing down at the end of the year. The countries such as the USA, England, Italy, and China published more articles and this cor-relates with the number of covid-19 cases.

3.
J Vector Borne Dis ; 2023 Jan; 60(1): 1-10
Article | IMSEAR | ID: sea-216905

ABSTRACT

Mites act as the vectors of zoonotic vector-borne disease scrub typhus caused by the rickettsial pathogen Orientia tsutsugamushi. In India, scrub typhus is transmitted by the mite Leptotrombidium deliense. Rodents are the reservoirs and support the spread of this disease. Sarcoptes scabiei or the itch mite is causing scabies which is a common skin infection in India. Dermatitis, trombiculosis, and mite dust allergy are common mite-borne diseases transmitted by Pyemotidae family. D. brevis folliculorum and Demodex brevis are two major mite species found on humans also causing a disease; “Demodicosis”, common in India. Dermanyssus gallinae, fowl mite causes pruritis in poultry birds, transmits infections to poultry workers when they come into contact with birds. There is a re-emergence of mite-borne diseases, especially scrub typhus, in many parts of India requiring urgent attention for its control. This review is aimed to update the available information on mites and mite transmitted diseases prevalent in India to highlight the importance of rodent and chigger mite vector control to prevent forthcoming mite-borne diseases in India.

4.
J Vector Borne Dis ; 2022 Oct; 59(4): 312-219
Article | IMSEAR | ID: sea-216897

ABSTRACT

Japanese encephalitis (JE) is a very serious public health problem in India and the conducive environment permit its emergence in non-endemic areas in the country. There are constant changes taking place in the pattern of current agricultural practices and vector breeding habitats which had far-reaching consequences on the epidemiology of JE and the severity of epidemic outbreaks today. Due to the continuous ecological changes taking place, vectors changed in their breeding dynamics, feeding, and resting behavior and started invading previously non-endemic areas. JE has recently spread to new territories due to land-use changes, including forest fragmentation and concentrated livestock production. Changes in the livestock population decreased the cattle pig ratio which enhanced the Japanese encephalitis virus (JEV) infection. This review brings forth the present widespread changes encountered that grossly impact the risk of infection in many places for the emergence of Japanese encephalitis and to address the implications for its control.

5.
J Vector Borne Dis ; 2022 Jan; 59(1): 12-21
Article | IMSEAR | ID: sea-216860

ABSTRACT

eas (Insecta, Siphonaptera) are important vectors of plague and murine typhus in many parts of the world. Currently, about 2700 flea species were described in the world. The most common vector flea Xenopsylla cheopis is found throughout India, but X. astia, and X. brasiliensis are found less and limited in distribution associated with the domestic rats such as Rattus rattus, R. norvegicus, Mus musculus, and Bandicota bengalensis. Bubonic plague is a major flea-borne disease caused by the bacterial pathogen Yersinia pestis, transmitted from rats to humans via the rodent flea, X. cheopis. A major outbreak of plague and high mortality occurred in India. After 1966 with the 3 decadal intervals, plague cases occurred only during the year 1994 reported in 5 different states (Gujarat, Maharashtra, Karnataka, Uttar Pradesh, Madhya Pradesh and New Delhi and subsequently plague cases occurred during 2002 and 2004 after the one-decade interval in Himachal Pradesh (2002). Another outbreak of bubonic plague was reported in Dangud village, Barkhot tehsil, Uttarkashi district, Uttarakhand during October 2004. Ctenocephalides fleas are common in cats and dogs, which are the main vectors of bacteria rickettsiae, such as Rickettsia typhi, R. felis, R. conorii, and Bartonella henselae. Molecular and serological evidence also confirms the presence of R. typhi, R. conorii R. felis and B. henselae pathogens in cats and other fleas in India. Flea bites and flea-borne dermatitis are common in men and pet animals. Because of the re-emergence of the plague, updated information on fleas and flea-borne diseases are essential to control the flea vectors and flea-borne diseases in India. Hence, this comprehensive review updates the available information on fleas and fleas transmitted diseases in India.

6.
Int J Pharm Pharm Sci ; 2020 Jul; 12(7): 87-89
Article | IMSEAR | ID: sea-206115

ABSTRACT

Migraine is a recurrent throbbing or pulsing headache with moderate to severe pain intensity. The pain is often one side of the head with nausea and weakness symptoms. Around 12 percent of Americans, 9 percent of Asians experiences migraine and the prevalence is highest among South Koreans (22.3%). The outcome of chronic migraine treatment can be quite disheartening, causing patients to feel out of options who have tried multiple treatments with no results. Poor efficacy, tolerability and safety of migraine preventive therapy in clinical practice lead to poor compliance and failure of therapy. The mean change in number or frequency of headache is considered as the outcome measure of migraine prevention therapy. Upon comparing all migraine prevention therapy, the Fremanezumab, Eptinezumab, Galcanezumab and Erenumab were considered as the front runner in controlling the severity and frequency of migraine. Among these drugs, Erenumab was most effective in controlling the frequency of migraine episodes as it produces more than 50 percent reduction in the mean number of monthly migraine days (MMD) over week 9-week 12. In addition to drug therapy, adequate rest, balanced diet, yoga and meditation will help patients to get rid of migraine severity. A multi-dimensional approach is essential for better control over migraine symptoms.

7.
Article | IMSEAR | ID: sea-215806

ABSTRACT

Thrombocytopenia is defined as platelet count < 1.5 lakhs/cumm. It is the commonest platelet abnormality observed in clinical practice with differentclinical expression. Thrombocytopenias in hematological malignancies are clonal proliferations of the malignant hematopoietic stem cells characterized by the accumulation of blasts principally in the marrow at the cost of impaired production of normal blood cells.The aim of the present study was to evaluate thrombocytopenia in cases of hematological malignancies with study of clinical profile and laboratory parameters in patients with thrombocytopenia.The present study had maximum numbers of patients were in the age group 20-39 years (8cases). Patients with platelet count more than 150 x 109/L, patients presented with massive hemorrhage, and who received massive colloid or crystalloid transfusion for volume loss are not included in our study. The maximum number of patients presenting with thrombocytopenia were males (18 cases).It was concluded that chronic lymphocytic leukemia are more common than other hematological malignancy cases

8.
Article | IMSEAR | ID: sea-213068

ABSTRACT

Background: All patients who presented to the emergency and trauma with a clinical evidence of hand injury were assessed based on the history and examination, mechanism of injury, common patterns of the injuries, management of the injuries and their functional outcome. The aim and objective were to study the mode, pattern, management and early outcome of hand injury cases attending Department of Emergency Medicine and trauma.Methods: This was a hospital based descriptive study, of patients presenting with hand injuries to the emergency department. The management plan was formulated and the outcomes of the treatment were assessed by limb function loss and Quick DASH 9 score.Results: Majority of our study population belonged to 16 to 35 years age group comprising of mostly males. Most of the incidents occurred within 50 km from our hospital. The mean duration to arrival at our hospital from site of injury was 2.71±2.61 hours. Road traffic accident in males and thermal burns in females were common. Fractures to phalanges of index and middle fingers were the most common type of injury. The average calculated Quick DASH 9 score was found to be 51.24±9.89.Conclusions: Hand injuries were found to be more prevalent in lower socioeconomic strata of the society with education status and occupation as major risk factors. Increased awareness and better implementation of traffic rules and better safety measures at workplace environment are the need of the hour to decrease the burden of hand injury.

9.
Article | IMSEAR | ID: sea-202619

ABSTRACT

Introduction: Pulmonary artery hypertension (PAH) whichcan be primary or secondary, has been found to be associatedwith chronic kidney disease, especially end stage renal disease.Finding prevalence of pulmonary hypertension in early stagesof chronic kidney disease is important because it createsvery high burden of cardio vascular morbidity and mortality.In this study we have assessed various factors associatedwith prevalence of pulmonary hypertension in patients withglomerular filtration rate less than 30ml/min per 1.73 metersquare on dialysis.Material and methods: This is a one year, hospital based,prospective observational study of patients aged more than 18years with GFR less than 30 ml/min per 1.73-meter square ondialysis, who were found to have pulmonary hypertension onechocardiography. The prevalence of pulmonary hypertensionin this group of patients and the risk factors in CKD associatedwith it are calculated followed by a descriptive analysis andinterpretation of the data.Results: The various factors we analyzed and p value forassociation of pulmonary hypertension in CKD for thepercentage of male and female in our study group is 0.241, fordistribution of the pulmonary hypertension among differentage groups is 0.503, for the significance of diabetic mellitus is0.595,for systemic hypertension is 0.206, for arterial venousfistula is 0.780,for superimposed infections 0.166, for volumeoverload is 0.560, for anemia is 0.780, for left ventriculardiastolic dysfunction is 0.662, for creatinine clearance is0.717,for duration of dialysis is 0.000. With above results,only association with significant p-value (0.000) in our studypopulation with pulmonary hypertensions longer duration.Conclusion: Prevalence of pulmonary hypertension in ourstudy is 22%. The risk factors like age,sex, diabetes, systemichypertension, AVF, superimposed infection, volume overload,anaemia, LVDD has no influence on pulmonary hypertensionin our study, only strong association that we have in our studypopulation with pulmonary hypertension with CKD is longerduration of dialysis.

10.
Article | IMSEAR | ID: sea-201664

ABSTRACT

Background: Stress can be defined as a physiological response to physical and mental demands. These stresses can negatively influence the performance and wellbeing of the employees. Police officers are a part of unique occupational population who are exposed various stressful conditions daily. This study attempts to explore factors influencing occupational stress faced by Policemen.Methods: The study was a cross sectional conducted among the policemen under three subdivisions of Villupuram, Tamilnadu. Operational police stress questionnaire was used to assess the stress levels with 20 statements which were then extracted into four dimensions by factor analysis.Results: By factor analysis stress was categorized into four factors or dimensions namely social and health related stress, time management stress, emotional stress and work-related stress.Conclusions: This study highlights that the major dimensions causing occupational stress among policemen which will form a framework for planning programs for stress management.

11.
Article | IMSEAR | ID: sea-201613

ABSTRACT

Background: Breast cancer is the second most common cancer among women in worldwide. One potentially important strategy in reducing breast cancer mortality is the use of screening methods such as breast self-examination (BSE), clinical breast examination, and mammography for early detection. This Study was conducted to assess knowledge and awareness regarding breast cancer and BSE among working women.Methods: A part of the interventional study was carried out among a total sample of 124 working women in Annamalai University. A pretested self-administered questionnaire was used to obtain information about the knowledge of breast cancer and BSE. The collected information was entered in Microsoft excel sheet and analysed using SPSS. One way ANOVA test has been applied to find out whether level of knowledge differs by age, education, occupation and BSE awareness.Results: Majority (67%) of women had inadequate knowledge on breast cancer and BSE. The education, occupation and breast self-awareness has influence on the knowledge level.Conclusions: The level of awareness on breast cancer and BSE among educated working women was low. Active steps and necessary interventions should be taken to increase awareness through health education program.

12.
Article | IMSEAR | ID: sea-192320

ABSTRACT

Introduction: Internet has become ubiquitous with the advent of smartphones. The dental fraternity keeps themselves updated and share knowledge through webinars, video conferences, research publications, etc. Hence, the internet serves as an imperative tool for dissemination of information. The usage of internet in dental education can be exploited to the fullest, especially due to the increased ownership rates of smartphones. Materials and Methods: A total of 490 students from four dental colleges in Tamil Nadu were asked to fill a close-ended questionnaire to assess the knowledge and attitude of dental students toward internet usage in smartphones. This study was conducted from November 2016 to January 2017. Results: The response rate was 100%. Almost all the students (98%) had knowledge on browsing. The percentage of internet use in smartphones were the highest (55.2%) followed by computers or laptops at home (26.5%). About 34.6% of students used internet in smartphones daily. More than half of the students (52.2%) used internet in smartphone at least 2–3 h a day. About one quarter (23.4%) of students used internet on a daily basis while 29.59% of students accessed the internet thrice a week for searching content related to dentistry. The preferred source for collecting dental-related information was through the internet (28.9%) and textbooks (28.5%). Conclusion: Dental students have considerable knowledge in using the internet for dental education and some of them utilize internet more frequently because of the possession of smartphones.

13.
Article | IMSEAR | ID: sea-192319

ABSTRACT

Introduction: Dental graduates have a professional responsibility of being competent in managing the complications in exodontia, a very commonly performed procedure. Aim: The aim of this paper was to assess the knowledge, attitude, and practice of senior dental students toward the management of complications in exodontia. Materials and Methods: Four hundred dental students participated in the study voluntarily. Verbal consent was obtained after elaborating the purpose of the study. A short validated questionnaire consisting of 12 close-ended multiple choice questions was distributed to all the students. The questionnaires were collected back and results from fully filled questionnaires were tabulated in Microsoft Excel 2007. Results: Nearly 93.4% of the students perform extractions in their practice on a routine basis. Among those 32.5% of the students have encountered complications, out of which only 20% of the students are confident in managing them. The remaining 64.8% of students who have not encountered complications are not confident in managing the same. Conclusion: This study revealed the need for increase in cases which will in turn help the students to transfer their theoretical knowledge into professional skills.

14.
J. bras. nefrol ; 41(2): 172-175, Apr.-June 2019. tab, graf
Article in English | LILACS | ID: biblio-1012543

ABSTRACT

ABSTRACT Introduction: The aim of this study was to analyze the presentation and management of major grade renal trauma in children. Method: A retrospective study was performed including data collected from the patients who were admitted in Pediatric surgery with major grade renal injury (grade 3 and more) from January 2015 to August 2018. Demography, clinical parameters, management, duration of hospital stay and final outcome were noted. Results: Out of 13 children (9 males and 4 females), with age range 2-12 years (mean of 8 years), reported self-fall was the commonest mode of injury followed by road traffic accident. The majority (10/13, 75%) had a right renal injury. Eight children had a grade IV injury, one had a grade V injury, and four children had grade III injury. Duration of hospital stay varied from 3 to 28 (mean of 11.7) days. Three children required blood transfusion. One child required image guided aspiration twice and two required pigtail insertion for perinephric collection. All the 13 children improved without readmission or need for any other surgical intervention. Conclusion: Children with major grade renal trauma due to blunt injury can be successfully managed without surgical intervention and minimal intervention may only be needed in select situations.


RESUMO Introdução: O objetivo deste estudo foi analisar a apresentação e tratamento de grande trauma renal em crianças. Método: Foi realizado um estudo retrospectivo incluindo dados coletados dos pacientes que foram internados na cirurgia pediátrica com lesão renal de grau importante (grau 3 ou mais) de janeiro de 2015 a agosto de 2018. Coletamos dados a respeito de demografia, parâmetros clínicos, manejo, tempo de internação e resultado final. Resultados: Das 13 crianças (9 homens e 4 mulheres) com faixa etária de 2-12 anos (média de 8 anos), a queda auto-relatada foi o modo de lesão mais comum seguido de acidente de trânsito. A maioria (10/13, 75%) apresentou lesão renal direita. Oito crianças tiveram uma lesão grau IV, uma apresentou uma lesão grau V e quatro crianças apresentaram lesão grau III. A duração da internação hospitalar variou de 3 a 28 (média de 11,7) dias. Três crianças necessitaram de transfusão de sangue. Uma criança necessitou de aspiração guiada por imagem duas vezes e duas inserções de dreno pigtail exigidas para coleções perinefréticas. Todas as 13 crianças melhoraram sem re-internação ou necessidade de qualquer outra intervenção cirúrgica. Conclusão: Crianças com trauma renal de alto grau devido a lesão contusa podem ser manejadas com sucesso sem intervenção cirúrgica, e intervenção mínima pode ser necessária apenas em situações selecionadas.


Subject(s)
Humans , Male , Female , Child, Preschool , Child , Wounds, Nonpenetrating/pathology , Wounds, Nonpenetrating/therapy , Early Medical Intervention , Conservative Treatment , Kidney/injuries , Wounds, Nonpenetrating/diagnostic imaging , Blood Transfusion , Accidental Falls , Injury Severity Score , Retrospective Studies , Follow-Up Studies , Treatment Outcome , Hospitals, University , Kidney/diagnostic imaging , Length of Stay
15.
Neurology Asia ; : 9-14, 2019.
Article in English | WPRIM | ID: wpr-822826

ABSTRACT

@#Background & Objective: About 95% of the adult population has been infected with varicella zoster virus (VZV). It can involve any part of the nervous system. This study aimed to determine the spectrum of neurological manifestations in patients with primary varicella zoster virus infection, its clinical course and prognosis. Methods: This was an observational study of patients who presented with primary VZV infection in the Institute of Neurology, Madras Medical college, Chennai between August 2015 and February 2018. Patients with neurological manifestations due to VZV reactivation were not included in the study. Detailed history, clinical examination, blood investigations, MRI brain and whole spine, CSF analysis including viral studies, nerve conduction studies, EEG were analysed. All primary VZV patients were found to have characteristic chickenpox rash and/or its scar. The course of disease and clinical outcome after treatment were studied. Results:Among the 22 patients, 10 patients presented with VZV meningoencephalitis, 4 patients with Guillain-Barré syndrome (GBS), 2 patients with meningoencephalitis with cerebellitis, 2 patients with cerebellitis, 1 patient as acute disseminated encephalomyelitis ( ADEM), 1 patient as neuromyelitis optica (NMO), Two patients had acute stroke like deficits due to VZV vasculopathy. GBS and ADEM patients were treated with intravenous immunoglobulin and NMO patient was treated with intravenous methylprednisolone and they clinically improved after 4 weeks. There were two mortalities (9%). Conclusion: Meningoencephalitis followed by GBS were the main manifestations of primary VZV from Chennai, India

16.
Pediatric Gastroenterology, Hepatology & Nutrition ; : 576-580, 2019.
Article in English | WPRIM | ID: wpr-760883

ABSTRACT

Meconium peritonitis as a cause of non-immune hydrops in neonates is rarely reported. Here we report such a rare occurrence. In our case, a routine antenatal scan at 25 weeks revealed isolated ascites. By 31 weeks of gestation, all features of hydrops were observed in scans. However, antenatal workup for immune and non-immune hydrops was negative. Subsequently, a preterm hydropic female baby was delivered at 32 weeks. She required intubation and ventilator support. An X-ray revealed calcification in the abdomen suggestive of meconium peritonitis. Ultrasound showed gross ascites, a giant cyst compressing the inferior vena cava, and minimal bilateral pleural effusion. Emergency laparotomy revealed meconium pellets and perforation of the ileum. Double-barrel ileostomy was performed, and the edema resolved and activity improved. The baby was discharged after 3 weeks. Ileostomy closure was done at follow-up. The baby is growing well.


Subject(s)
Female , Humans , Infant, Newborn , Pregnancy , Abdomen , Ascites , Edema , Emergencies , Follow-Up Studies , Hydrops Fetalis , Ileostomy , Ileum , Intubation , Laparotomy , Meconium , Peritonitis , Pleural Effusion , Ultrasonography , Vena Cava, Inferior , Ventilators, Mechanical
17.
Article | IMSEAR | ID: sea-185286

ABSTRACT

Background :Cerebral venous thrombosis (CVT) is one of the common causes of stroke in young people. CVT is a disease with potentially serious consequences and usually affecting young to middle-aged people. Strokes in the young account for nearly 30% of all cases of stroke in India and cerebral venous thrombosis (CVT) accounts for 10-20% of these cases Accurate and prompt diagnosis of CVT is crucial because timely and appropriate therapy can reverse the disease process and significantly reduce the risk of acute complications and long-term squelae. CVT can be caused by a number of prothrombotic states and disorders of clotting system such as inherited causes like Protein C resistance secondary to Factor V Leiden polymorphism, Protein C and S resistance, and antithrombin III deficiency. Many other etiological factors like drugs ,infections,etc. Aim: To analyse the clinical profile and the outcome of young males with CVT. Methodology: This prospective study was carried out over a period of one year in the Neurology department in whom the diagnosis were confirmed by magnetic resonance imaging (MRI), MRV venogram , plain/contrast CT were included in the study. A total of 42 patients were enrolled for the study in the period of one year. The patients demographic details including the diabetic and hypertensive status along with their family history was obtained by using a detailed questionnaire. Results: Majority of them were between the age group of 18 - 35 years. Headache was found to be the most common symptom followed by nausea vomiting and seizures. Majority of the patients with CVThad a history of alcoholism in this study. In our study exactly 33% were unknown factors, 32% Alcohol, 28% Dehydration, 7% infections. Conclusion: . Accurate and prompt diagnosis of CVT is crucial because timely and appropriate therapy can reverse the disease process and significantly reduce the risk of acute complications and long-term sequelae

18.
Article | IMSEAR | ID: sea-185042

ABSTRACT

Mid–sagittal diameter of 3rd to 7th cervical verteae, is the single most important measurement, which highly correlates with the risk of developing neurological deficit in patients with cervical spondylosis. Mid–sagittal diameter varies with the sex, race, geographical area, nutrition, built of the target population. In this study, we measured the midsagittal diameter in x–ray cervical spine lateral view and in anatomical cervical bone specimens in our local population. We found baseline value of mid–sagittal in our local population by measuring mid–sagittal diameter of C3 to C7 in cadavers. We found that, the midsagittal diameter highly correlates with the risk of developing cervical spondylotic myelopathy. Although radiographic measurement of midsagittal diameter gives magnification of approximately 22%, it can be safely used as a screening tool in outpatient department.

19.
J. bras. nefrol ; 40(3): 261-265, July-Sept. 2018. tab
Article in English | LILACS | ID: biblio-975915

ABSTRACT

ABSTRACT Introduction: Children with solitary functioning kidney (SFK) are prone to develop long term problems, which are not well represented in the literature. The extent to which the presence of associated congenital anomalies of kidney and urinary tract (CAKUT) further de-stabilize renal function is to be addressed. Objective: This study was conducted to evaluate the etiology, presentation, presence of CAKUT, and renal damage in children with SFK. Methods: All children with SFK who presented to the department of pediatric surgery from March 2014 to May 2016 were included in the study. Children with malignancy were excluded from the study. Results: Of the 20 patients with SFK, 14 (70%) had primary SFK (8 with agenesis and 6 with multicystic dysplastic kidney), 6 (30%) belonged to secondary SFK group, among them 3 had pelviureteric junction obstruction, 2 had posterior urethral valves and 1 had vesicoureteric reflux. Eight (40%) had associated CAKUT, 4 (20%) were asymptomatic while 8 (40%) had UTI and 6 (30%) had hypertension. Ten (50%) patients had reduced glomerular filtration rate (GFR) suggesting compromised renal function. Conclusion: Children with SFK have high morbidity especially when associated with ipsilateral CAKUT. Long-term periodical follow up is essential in these patients to improve clinical outcome.


RESUMO Introdução: Crianças com rim solitário funcional (RSF) tendem a desenvolver problemas de longo prazo, que não são bem representados na literatura. Devemos abordar o quanto a presença de malformações congênitas do rim e do trato urinário (CAKUT) desestabiliza ainda mais a função renal. Objetivo: Este estudo foi realizado para avaliar a etiologia, apresentação, presença de CAKUT e dano renal em crianças com RSF. Métodos: Todas as crianças com RSF que se apresentaram no departamento de cirurgia pediátrica de março de 2014 a maio de 2016 foram incluídas no estudo. Crianças com doença maligna foram excluídas do estudo. Resultados: dos 20 pacientes com RSF, 14 (70%) tinham RSF primário (8 com agenesia e 6 com rim displásico multicístico), 6 (30%) pertenciam ao grupo RSF secundário, dentre eles 3 tinham obstrução da junção pelveuretérica, 2 tinham valvas uretrais posteriores e 1 refluxo vesico-uretral. Oito (40%) tinham ACRTU associado, 4 (20%) estavam assintomáticos, enquanto 8 (40%) tinham ITU e 6 (30%) tinham hipertensão. Dez (50%) pacientes apresentaram redução da taxa de filtração glomerular (TFG), sugerindo comprometimento da função renal. Conclusão: Crianças com RSF apresentam alta morbidade, especialmente quando associadas à CAKUT ipsilateral. O acompanhamento periódico a longo prazo é essencial nesses pacientes para melhorar o resultado clínico.


Subject(s)
Humans , Male , Female , Infant, Newborn , Infant , Urogenital Abnormalities/diagnosis , Urogenital Abnormalities/etiology , Vesico-Ureteral Reflux/diagnosis , Vesico-Ureteral Reflux/etiology , Solitary Kidney/complications , Prospective Studies
20.
JPAD-Journal of Pakistan Association of Dermatologists. 2018; 28 (2): 224-232
in English | IMEMR | ID: emr-206703

ABSTRACT

Objective To compare the resurfacing effect of microdermabrasion versus glycolic acid peeling in the treatment of acne scars


Methods A total of 80 patients were selected randomly and divided into two groups A [treated with microdermabrasion] and B [treated with glycolic acid peeling]. Data were coded and analyzed


Results Of the 80 participants, 56 completed all 6 sessions. Among those 56 patients, 24 patients belonged to group A and 32 patients belonged to group B. In group A, good improvement was noted in 16.7 percent of the patients, 67 percent showed fair improvement, 12.5 percent showed poor improvement and 4.2 percent had no change after 6 sessions. In group B, 3 percent of the patients showed excellent improvement, 3 percent showed good improvement, 81.3 percent showed fair improvement, 6.25 percent showed poor improvement and no change was noted in 6.25 percent of the patients


Conclusion This study infers that superficial scars showed greater improvement with microdermabrasion while reduction in active acne lesions was much more with glycolic acid peel. However, no statistically significant differences were found between the outcomes of both therapeutic modalities

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